Results 141 to 150 of about 764,224 (312)

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement   +12 more
wiley   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

open access: yesAdvanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery   +10 more
wiley   +1 more source

Mucosa‐Interfacing Capsule for In Situ Sensing the Elasticity of Biological Tissues

open access: yesAdvanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
A fundamental mechanism of palpating soft materials is reported to sense deep tissue elasticity in situ with minimal invasion using the interaction between the robot palpation unit and soft tissues. Both the robot locomotion and elasticity sensing functions are remotely controlled by external magnetic fields, while the sensing data are wirelessly ...
Kiyoung Kim   +10 more
wiley   +1 more source

A High Throughput Microfluidic Approach for the Continuous Manufacture of Ibuprofen Nanocrystals

open access: yesAdvanced Materials Technologies, EarlyView.
A robust, continuous manufacturing platform using a high‐throughput microfluidic reactor addresses key scalability challenges in pharmaceutical production. This process efficiently generates crystalline ibuprofen nanoparticles with superior control over size and distribution.
Shorooq Abukhamees   +5 more
wiley   +1 more source

Steatosis is not associated with increased risk of chemotherapy-associated liver injury in metastatic colorectal cancer [PDF]

open access: diamond
Robert H. Squires   +7 more
openalex   +1 more source

Femtosecond‐Laser‐Fabricated 3D CYTOP Microfluidic Chips Enabling Super‐Resolution Live Imaging of Cell Behavior in Confined Microspaces

open access: yesAdvanced Materials Technologies, EarlyView.
Using two‐photon polymerization of SU‐8 together with mold processing allowed the creation of defect‐free, flexible 3D microfluidic structures with sub‐micrometer precision in CYTOP. The fabricated CYTOP microfluidic chips enabled super‐resolution imaging of cancer cells in the microchannels, clearly visualizing previously undetectable fine structural ...
Koji Sugioka   +16 more
wiley   +1 more source

Exploration of mRNA-modifying METTL3 oncogene as momentous prognostic biomarker responsible for colorectal cancer development

open access: yesOpen Medicine
Naveed Muhammad   +9 more
doaj   +1 more source

Association of Sleep Disturbance With Survival After Colorectal Cancer Diagnosis: Results From the ColoCare Study. [PDF]

open access: yesCancer Med
Peoples AR   +18 more
europepmc   +1 more source

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