Results 161 to 170 of about 764,224 (312)

A novel β-carboline alkaloid derivative targeting MDM2-p53 pathway suppresses colorectal cancer progression [PDF]

open access: hybrid
Fanbin Zeng   +11 more
openalex   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

PEPCOL: a GERCOR randomized phase II study of nanoliposomal irinotecan PEP02 (MM‐398) or irinotecan with leucovorin/5‐fluorouracil as second‐line therapy in metastatic colorectal cancer [PDF]

open access: gold, 2016
Benoist Chibaudel   +17 more
openalex   +1 more source

FAPα+ Macrophages Orchestrate Immune Evasion in Multiple Myeloma by Dual Regulation of PD‐L1 and T Cell Senescence

open access: yesAdvanced Science, EarlyView.
ABSTRACT Multiple myeloma (MM) is a hematologic malignancy driven by clonal expansion of malignant plasma cells. Despite the long‐term disease control achieved with immunotherapies in some patients, treatment resistance remains a major cause of disease relapse.
Huiyao Gu   +15 more
wiley   +1 more source

Examining the Outcomes of Palliative Oophorectomy of Ovarian Metastases in de-Novo Metastatic Colorectal Cancer and Its Association with RAS Mutation Status: Insights from a Single-Institution Perspective

open access: yesCancer Management and Research
Tala Alawabdeh,1 Maram Ismat Al-Ya’goub,1 Khair Hamo,2 Yosra Almasri,1 Rim Turfa,1 Saif Alnassarwin,3 Hadeel Isam Masadeh,4 Rnad Khader,1 Teeba Mubaydeen2 1Department of Medical Oncology, King Hussein Cancer Center, Amman, Jordan; 2Department of internal
Alawabdeh T   +8 more
doaj  

Macronutrient quality and colorectal cancer outcomes: evidence from the PLCO screening trial. [PDF]

open access: yesFront Nutr
Feng D   +10 more
europepmc   +1 more source

ETV4 interacts with LOXL2 to induce epigenetic activation of NID1 during colorectal cancer progression [PDF]

open access: gold
Tinghui Jiang   +13 more
openalex   +1 more source

METTL1‐Mediated M7G tRNA Modification Promotes Residual Liver Regeneration After Hepatectomy via Translational Control

open access: yesAdvanced Science, EarlyView.
METTL1 and its mediated m7G tRNA modification are significantly up‐regulated after partial hepatectomy (PHx). Overexpression of METTL1 improves the efficiency of liver regeneration after PHx, increases the proliferation of hepatocytes, and accelerates the recovery of liver function.
Manling Huang   +18 more
wiley   +1 more source

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