Results 11 to 20 of about 1,039,677 (302)
Current Oncology, 2023 Deficient mismatch repair (dMMR)/microsatellite instability-high (MSIH) colorectal cancer is resistant to conventional chemotherapy but responds to immune checkpoint inhibition (ICI).
Alan Su, Rodrigo Pedraza, Hagen Kennecke
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Physiologia, 2023 With colon cancer being one of the deadliest and most common cancers, understanding the mechanisms behind colon cancer is crucial in improving therapies. One of the newest approaches in cancer research is the concept of proteogenomics. While genomic data
Soumyadev Sarkar
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Carcinoma Rectum with Prostate and Urinary Bladder Metastasis- A Rare Case Report [PDF]
Journal of Clinical and Diagnostic Research, 2021 Tumours of the colon and rectum are one of the most common malignancies worldwide. In India, its incidence is less compared to the developed countries however,recently it has increased from past few decades due to sedentary lifestyle and more ...
Rabbavijaya Sowjanya Lakshmi +3 more
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Frontiers in Oncology, 2022 ObjectiveEndoscopic ultrasound (EUS) is an established method for staging of colorectal cancer. Nevertheless, prior assessments of its T stage accuracy have been limited, particularly ambiguity in assessed T3 and T4a stage. This study was to characterize
Chaoqun Han +6 more
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, 2021 Psychological issues around colorectal cancer (CRC) can emerge from the point CRC is suspected, through treatment, to living with or beyond cancer. One-third of patients report high levels of anxiety while undergoing investigations for suspected cancer, and emotional difficulties, particularly anxiety and fear of recurrence, can persist for years ...
Miles, Anne, Redeker, Claudia
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BMJ, 2013 This is the final version of the article. Available from the publisher via the DOI in this record. ; This is one of a series of occasional articles highlighting conditions that may be more common than many doctors realise or may be missed at first presentation.
Hamilton, W, Coleman, MG, Rubin, G
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Cancer Research, Statistics, and Treatment, 2021 Background: Colorectal cancers (CRCs) arise due to the progression of acquired or hereditary premalignant lesions. Therefore, an early diagnosis is essential to devise suitable preventive strategies against CRC.
Puja Bhavesh Jarwani +3 more
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Mouse models of colorectal cancer. [PDF]
, 2011 Colorectal cancer is one of the most common malignancies in the world. Many mouse models have been developed to evaluate features of colorectal cancer in humans. These can be grouped into genetically-engineered, chemically-induced, and inoculated models.
Koeffler, H Phillip +2 more
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BH3 mimetic ABT-737 sensitizes colorectal cancer cells to ixazomib through MCL-1 downregulation and autophagy inhibition. [PDF]
, 2016 The proteasome inhibitor MLN9708 is an orally administered drug that is hydrolyzed into its active form, MLN2238 (ixazomib). Compared with Bortezomib, MLN2238 has a shorter proteasome dissociation half-life and a lower incidence and severity of ...
Barkhouse, Darryll +7 more
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Does ursodeoxycholic acid change the proliferation of the colorectal mucosa? A randomized, placebo-controlled study [PDF]
, 2003 Background: In animal models ursodeoxycholic acid (UDCA) showed a chemoprotective effect against colon cancer. To explain this, a reduced proliferation of the colorectal mucosal proliferation was suggested.
Diebold, J. +6 more
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