Results 161 to 170 of about 5,332,530 (372)

Preoperative T staging using CT colonography with multiplanar reconstruction for very low rectal cancer

BMC Cancer, 2017
Background Preoperative T staging of lower rectal cancer is an important criterion for selecting intersphincteric resection (ISR) or abdominoperineal resection (APR) as well as selecting neoadjuvant therapy.
Dai Shida, Gen Iinuma, Akira Komono, Hiroki Ochiai, Shunsuke Tsukamoto, Mototaka Miyake, Yukihide Kanemitsu   +6 more
doaj   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Klotho negatively regulated aerobic glycolysis in colorectal cancer via ERK/HIF1α axis

Cell Communication and Signaling, 2018
Background Klotho (KL) was originally characterized as an aging suppressor gene, and has been identified as a tumor suppressor gene in a variety of cancers, including colorectal cancer.
Qingguo Li, Yaqi Li, Lei Liang, Jing Li, Dakui Luo, Qi Liu, Sanjun Cai, Xinxiang Li   +7 more
doaj   +1 more source

Cancer Awareness in Alternative Settings: Lessons Learned and Evaluation of the Barbershop Men’s Health Project

, 2012
Prostate and colorectal cancer are two of the leading causes of cancer deaths among African American men. This study describes lessons learned from the development, implementation and evaluation of a culturally appropriate, barbershop-based intervention ...
Debnam, Katrina, Holt, Cheryl L., Jeames, Sanford, Litaker, Mark S., Schoenberger, Yu-Mei, Simons, Virgil, Southward, Penny, Wynn, Theresa A.   +7 more
core  

The contribution of serum enzymes and carcinoembryonic antigen to the early diagnosis of metastatic colorectal cancer [PDF]

, 1975
E.H. Cooper, Robert D. Turner, Linda Steele, Alan Nevill, Alan Mackay   +4 more
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Comparative educational approaches to screening for colorectal cancer. [PDF]

, 1978
Thomas W Elwood, Andrew Erickson, Stephen F. Lieberman   +2 more
openalex   +1 more source

Serum enzymes in colorectal cancer [PDF]

, 1979
Peter Beck, A. Belfield, R J Spooner, Leslie H. Blumgart, C B Wood   +4 more
openalex   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source