Results 171 to 180 of about 3,531,408 (290)
Colorectal cancer and tumor vaccines (Review). [PDF]
Ma J, Xiang C, Xia D.
europepmc +1 more source
Cell‐Selective Delivery of RIBOTACs via an Anti‐EGFR Nanobody for Pancreatic Cancer Treatment
This study introduces an innovative strategy for the tumor‐selective catalytic degradation of oncogenic non‐coding RNA by interfacing a ribonuclease‐recruiting small molecule (RIBOTAC) with an EGFR‐targeting nanobody via a CTSB (Cathepsin B)‐responsive linker.
Tianli Luo +15 more
wiley +1 more source
Genomic Landscape of Early-Onset Colorectal Cancer: A Comparative Analysis With Average-Onset Metastatic Colorectal Cancer in a Real-World NGS Cohort. [PDF]
Shin JE +7 more
europepmc +1 more source
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen +14 more
wiley +1 more source
Preoperative nutrition in colorectal cancer surgery: mini review. [PDF]
Estrada-Moya F +9 more
europepmc +1 more source
Enhancing Super‐Resolution Spatial Transcriptomics Data by Transfer Learning
SpotZoomer employs a transfer‐learning‐based strategy to enhance the resolution of Visium data by leveraging available high‐resolution priors. The resulting super‐resolved maps enable sharper delineation of cell boundaries and more precise inference of cell–cell communication patterns that would otherwise remain obscured at native resolution.
Xiaoyu Li, Lihua Zhang, Wenwen Min
wiley +1 more source
Positive Predictive Value of Symptoms for Early-Onset Colorectal Cancer. [PDF]
Chubak J +11 more
europepmc +1 more source
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng +13 more
wiley +1 more source
Association of coffee intake with risk of all-cause and colorectal cancer-specific mortality among individuals with colorectal cancer in the Multiethnic Cohort Study. [PDF]
Benson KRK +10 more
europepmc +1 more source

