Results 191 to 200 of about 5,673,125 (350)
Targeting Myc-driven stress vulnerability in mutant KRAS colorectal cancer [PDF]
, 2022 Hang Ruan, Brian J. Leibowitz, Yingpeng Peng, Lin Shen, Lujia Chen, Chaoyuan Kuang, Robert E. Schoen, Xinghua Lu, Lin Zhang, Jian Yu +9 moreopenalex +1 more sourcePeptide Amphiphiles Hitchhike on Endogenous Biomolecules for Enhanced Cancer Imaging and Therapy
Advanced Materials, EarlyView.Weakly assembled peptide amphiphile nanostructures disassemble in circulation and reassemble with blood biomolecules, mainly lipoproteins. Binding to blood biomolecules prolongs blood circulation and improves accumulation in solid tumors. In the tumor microenvironment, peptide amphiphiles assemble with cholesterol‐rich domains of cell membranes ...Li Xiang, Morgan R. Stewart, Kailin Mooney, Mingchong Dai, Samuel Drennan, Samantha Holland, Arnaud Quentel, Sinan Sabuncu, Benjamin R. Kingston, Isabel J. Dengos, Karla Bonic, Florian Goncalves, Xin Yi, Michael I. Henderson, Srivathsan Ranganathan, Bruce P. Branchaud, Leslie L. Muldoon, Ramon F. Barajas Jr, Jared M. Fischer, Adem Yildirim +19 morewiley +1 more sourceTailoring Advanced Metal‐Based Nanomedicines for Adaptable Nanodynamic Disease Therapies and Theranostics
Advanced Materials, EarlyView.This review summarizes recent advances in metal‐based nanomaterials (MBNs) as multifunctional platforms for next‐generation diagnostics and nanodynamic therapies (NDTs), highlighting their structural tunability, diverse therapeutic modalities, and broad biomedical applications in oncology and infectious disease control.Qihang Ding, Wenhao Li, Ling Mei, Suling Luo, Jing Tao, Chongxiu Shi, Hongping Yang, Wei Feng, Yungchang Chen, Yu Chen, Jong Seung Kim, Xue Shen +11 morewiley +1 more sourceWild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer [PDF]
, 2008 Rafael G. Amado, Michael Wolf, Marc Peeters, Eric Van Cutsem, Salvatore Siena, Daniel J. Freeman, Todd Juan, Robert Sikorski, Sid Suggs, Robert Radinsky, Scott D. Patterson, David Chang +11 moreopenalex +1 more sourceCetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer.
New England Journal of Medicine, 2004 D. Cunningham, Y. Humblet, S. Siena, D. Khayat, H. Bleiberg, A. Santoro, D. Bets, M. Mueser, A. Harstrick, C. Verslype, I. Chau, E. Van Cutsem +11 moresemanticscholar +1 more sourceMucosa‐Interfacing Capsule for In Situ Sensing the Elasticity of Biological Tissues
Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.A fundamental mechanism of palpating soft materials is reported to sense deep tissue elasticity in situ with minimal invasion using the interaction between the robot palpation unit and soft tissues. Both the robot locomotion and elasticity sensing functions are remotely controlled by external magnetic fields, while the sensing data are wirelessly ...Kiyoung Kim, Steven Edwards, Kyle Fuxa, Honglu Lin, Shreya Shrestha, Hanwen Fan, Nick Diaz, Joel Berinstein, Rishi Naik, Yuxiao Zhou, Xiaoguang Dong +10 morewiley +1 more sourceMutational signature in colorectal cancer caused by genotoxic pks+E. coli
Nature, 2020 Cayetano Pleguezuelos-Manzano, Jens Puschhof, Axel K M Rosendahl Huber, Arne van Hoeck, H. Wood, Jason Nomburg, C. Gurjao, F. Manders, G. Dalmasso, P. Stege, F. Paganelli, Maarten H. Geurts, J. Beumer, Tomohiro Mizutani, Y. Miao, Reinier van der Linden, S. van der Elst, J. C. P. E. L. M. F. J. M. C. R. H. M. J. G. C. C. E. Ambrose Arumugam Baple Bleda Boardman-Pretty Boiss, J. Ambrose, P. Arumugam, E. Baple, M. Bleda, F. Boardman-Pretty, J. Boissiere, C. Boustred, H. Brittain, M. Caulfield, G. Chan, C. Craig, L. Daugherty, A. de Burca, A. Devereau, G. Elgar, R. E. Foulger, T. Fowler, P. Furió-Tarí, J. Hackett, D. Halai, A. Hamblin, S. Henderson, J. Holman, T. Hubbard, K. Ibáñez, R. Jackson, L. J. Jones, D. Kasperaviciute, M. Kayikci, L. Lahnstein, L. Lawson, S. Leigh, I. Leong, F. J. Lopez, F. Maleady-Crowe, J. Mason, E. McDonagh, L. Moutsianas, M. Mueller, N. Murugaesu, A. Need, C. Odhams, C. Patch, D. Perez-Gil, D. Polychronopoulos, J. Pullinger, T. Rahim, A. Rendon, P. Riesgo-Ferreiro, T. Rogers, M. Ryten, K. Savage, K. Sawant, R. Scott, A. Siddiq, A. Sieghart, D. Smedley, K. Smith, A. Sosinsky, W. Spooner, H. E. Stevens, A. Stuckey, R. Sultana, E. Thomas, S. Thompson, C. Tregidgo, A. Tucci, E. Walsh, S. Watters, M. Welland, E. Williams, K. Witkowska, S. Wood, M. Zarowiecki, K. Garcia, J. Top, R. Willems, M. Giannakis, R. Bonnet, P. Quirke, M. Meyerson, E. Cuppen, R. van Boxtel, H. Clevers +101 moresemanticscholar +1 more sourceMicroneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics
Advanced Materials Technologies, EarlyView.Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly +12 morewiley +1 more source
