Results 311 to 320 of about 5,582,484 (376)

An MOF‐Enhanced Anti‐Fouling Immunoprobe Platform for Efficient Direct Screening of Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This work introduces an electrochemical sensing method that employs an innovative platform based on metal‐organic framework (MOF) for detecting biomarkers. The platform integrates an antifouling surface, oriented antibody immobilization, and an enhanced electron transfer layer.
Wenjuan Yang   +10 more
wiley   +1 more source

Bioinformatics mining and experimental validation of prognostic biomarkers in colorectal cancer. [PDF]

open access: yesDiscov Oncol
Huang F   +10 more
europepmc   +1 more source

STK25 Loss Augments Anti‐PD‐1 Therapy Efficacy by Regulating PD‐L1 Stability in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study demonstrates that STK25 depletion facilitates CRC immune escape through the inhibition of PD‐L1 Ser283 phosphorylation‐mediated ubiquitination, and promotes tumor growth. Furthermore, these findings identify STK25 as a potential therapeutic target to trigger antitumor immunity and promote immunotherapy efficacy. Abstract Tumor immune evasion
Xiaowen Qiao   +20 more
wiley   +1 more source

Computational screening of phytochemicals targeting mutant KRAS in colorectal cancer. [PDF]

open access: yesSci Rep
Arooj M   +15 more
europepmc   +1 more source

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

open access: yesAdvanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han   +24 more
wiley   +1 more source

Dynamic Prognostic Models for Colorectal Cancer With Liver Metastases.

open access: yesJAMA Netw Open
Chen Q   +6 more
europepmc   +1 more source

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