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Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review.

Journal of the American Medical Association (JAMA), 2021
Importance Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide with more than 1.85 million cases and 850 000 deaths annually. Of new colorectal cancer diagnoses, 20% of patients have metastatic disease at presentation and
Leah H. Biller, D. Schrag
semanticscholar   +1 more source

Colorectal cancer

Medical Journal of Australia, 1999
Colorectal cancer is the leading cause, after lung cancer, of death from cancer in Australia. About 50% of colorectal cancers are attributed to dietary factors and about 15%-20% to genetic factors, including high risk familial syndromes. The most common presenting symptoms are rectal bleeding (left-sided cancers) and iron-deficiency anaemia (right ...
P J, Prichard, J J, Tjandra
  +9 more sources

Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement.

Journal of the American Medical Association (JAMA), 2021
Importance Colorectal cancer is the third leading cause of cancer death for both men and women, with an estimated 52 980 persons in the US projected to die of colorectal cancer in 2021. Colorectal cancer is most frequently diagnosed among persons aged 65
K. Davidson   +17 more
semanticscholar   +1 more source

Colorectal cancer

The Lancet, 2014
More than 1·2 million patients are diagnosed with colorectal cancer every year, and more than 600,000 die from the disease. Incidence strongly varies globally and is closely linked to elements of a so-called western lifestyle. Incidence is higher in men than women and strongly increases with age; median age at diagnosis is about 70 years in developed ...
Hermann, Brenner   +2 more
openaire   +3 more sources

Colorectal Cancer

Clinical Oncology, 2016
Essential facts Colorectal cancer is the fourth most common cancer in the UK, after breast, lung and prostate cancer, with around 41,600 people in the UK diagnosed each year. It is the second most common cause of cancer death in the UK. According to the charity Bowel Cancer UK, 98% of people diagnosed at the earliest stage will survive, while less than
D C, Gilbert, S J, Falk
openaire   +4 more sources

Colorectal cancer

The Lancet, 2010
Substantial progress has been made in colorectal cancer in the past decade. Screening, used to identify individuals at an early stage, has improved outcome. There is greater understanding of the genetic basis of inherited colorectal cancer and identification of patients at risk.
David, Cunningham   +6 more
openaire   +2 more sources

Hereditary Colorectal Cancer

Hematology/Oncology Clinics of North America, 2022
Around 10% to 16% of colorectal cancer patients have a pathogenic variant in a cancer susceptibility gene. Some of these variants are in cancer genes that are associated with colorectal cancer while others are not. The hereditary colorectal cancer syndromes can be divided into two major categories, the nonpolyposis and the polyposis conditions.
Heather, Hampel   +3 more
openaire   +2 more sources

Colorectal cancer

The Lancet, 2005
Every year, more than 945000 people develop colorectal cancer worldwide, and around 492000 patients die. This form of cancer develops sporadically, in the setting of hereditary cancer syndromes, or on the basis of inflammatory bowel diseases. Screening and prevention programmes are available for all these causes and should be more widely publicised ...
Jürgen, Weitz   +5 more
openaire   +4 more sources

A Cell-free DNA Blood-Based Test for Colorectal Cancer Screening.

New England Journal of Medicine
BACKGROUND Colorectal cancer is the third most diagnosed cancer in adults in the United States. Early detection could prevent more than 90% of colorectal cancer-related deaths, yet more than one third of the screening-eligible population is not up to ...
Daniel C. Chung   +12 more
semanticscholar   +1 more source

Colorectal cancer screening

Current Opinion in Oncology, 1998
Comprehensive evidence-based guidelines for screening and surveillance for colorectal cancer were published in 1997. Backed by compelling scientific data from recently completed controlled trials and case-control studies, these guidelines recommend annual fecal occult blood test screening plus periodic flexible sigmoidoscopy about every 5 years for ...
openaire   +2 more sources

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