Results 81 to 90 of about 648,498 (303)

Multiple rapidly growing desmoid tumors that were difficult to distinguish from recurrence of rectal cancer

open access: yesWorld Journal of Surgical Oncology, 2017
Background Intra-abdominal desmoid tumors are usually slow growing and solitary, but multifocal desmoid tumors develop on rare occasions. Diagnosing desmoid tumors before histological examination of a surgical biopsy is often difficult. In particular, if
Koki Nakanishi   +6 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

A preoperative MRI pelvic multiparameter nomogram for predicting sphincter preservation and operative difficulty in laparoscopic total mesorectal excision for ultra-low rectal cancer

open access: yesBMC Surgery
Background Sphincter preservation (SP) during laparoscopic total mesorectal excision (LaTME) for low rectal cancer is challenged by a deep, narrow pelvis. Robust, MRI-based predictors for both SP success and operative difficulty are lacking.
Haipeng Jin   +4 more
doaj   +1 more source

Evaluation of the utility of a nomogram for predicting lymph node metastasis in T1 colorectal cancer in shared decision-making in clinical practice: a survey-based study [PDF]

open access: yesAnnals of Coloproctology
Purpose In 2019, we reported a novel nomogram to predict lymph node metastasis (LNM) in T1 colorectal cancer. Herein, we conducted a survey-based study to evaluate the clinical utility of this nomogram in determining the need for additional surgery after
Hyeon Seung Kim   +10 more
doaj   +1 more source

FOXE1 represses cell proliferation and Warburg effect by inhibiting HK2 in colorectal cancer

open access: yesCell Communication and Signaling, 2020
Background Low expression of FOXE1, a member of Forkhead box (FOX) transcription factor family that plays vital roles in cancers, contributes to poor prognosis of colorectal cancer (CRC) patients.
Weixing Dai   +8 more
doaj   +1 more source

Nutritional and inflammatory measures predict survival of patients with stage IV colorectal cancer

open access: yesBMC Cancer, 2020
Background This study aimed to evaluate the prognostic impact of nutritional and inflammatory measures (controlling nutritional status (CONUT) score, prognostic nutritional index (PNI), and modified Glasgow prognostic score (mGPS)) on overall survival ...
Yasuyuki Takamizawa   +8 more
doaj   +1 more source

Cost-effectiveness analysis of colorectal cancer screening with stool DNA testing in intermediate-incidence countries [PDF]

open access: yes, 2006
Background: The aim of this study is to compare the cost-effectiveness of screening with stool DNA testing with that of screening with other tools (annual fecal occult blood testing, flexible sigmoidoscopy every 5 years, and colonoscopy every 10 years ...
Chen, Tony   +13 more
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Identification of PANoptosis associated lncRNAs associated with clinical prognosis and immune infiltration microenvironment in colon adenocarcinoma

open access: yesDiscover Oncology
Early diagnosis and disease management based on risk stratification have a very positive impact on colon adenocarcinoma (COAD) prognosis. It is of positive significance to further explore risk stratification of COAD patients and identify predictive ...
Yangyang Wang   +6 more
doaj   +1 more source

Expression of Foxp3 in colorectal cancer but not in Treg cells correlates with disease progression in patients with colorectal cancer

open access: yes, 2013
Background: Regulatory T cells (Treg) expressing the transcription factor forkhead-box protein P3 (Foxp3) have been identified to counteract anti-tumor immune responses during tumor progression. Besides, Foxp3 presentation by cancer cells itself may also
Kim, Mia   +25 more
core   +1 more source

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