Results 191 to 200 of about 350,814 (249)

Somatic whole exome sequencing of colorectal carcinoma in young patients from sub-Saharan Africa reveals novel insights. [PDF]

J Pathol Clin Res
Aldera AP, Owusu D, Biral L, Pillay K, Boutall A, Dave S, Ramesar R.   +6 more
europepmc   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Functionalized turmeric nanovesicles for precision delivery of doxorubicin in colorectal carcinoma treatment. [PDF]

Front Pharmacol
Meng C, Yi X, Duan M, Mahal A, Zhang Z, Ren J, Chen M, Yang L, Xu M, Obaidullah AJ, Song L, Li S, Wang C.   +12 more
europepmc   +1 more source

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Prognostic role of Ki-67 in colorectal carcinoma: Development and evaluation of machine learning prediction models. [PDF]

World J Clin Oncol
Zeng DT, Li MJ, Lin R, Huang WJ, Li SD, Huang WY, Li B, Li Q, Chen G, Jiang JS.   +9 more
europepmc   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Sarcopenia as a Prognostic Factor for the Outcomes of Surgical Treatment of Colorectal Carcinoma. [PDF]

Healthcare (Basel)
Leščák Š, Košíková M, Jenčová S.   +2 more
europepmc   +1 more source

Structural and Biological Insights Into Copper(I) Phosphane Complexes With Boron‐Phenylated Poly(3‐(CF3)Pyrazolyl)‐ and Poly(6‐(CF3)‐2‐pyridyl)‐Borates

Chemistry – A European Journal, EarlyView.
This study reports six new copper(I) complexes with unusual coordination and strong anticancer activity against a panel of human cancer cell lines derived from different solid tumors. The most active compounds outperform cisplatin, even in resistant cells, by inhibiting protein disulfide isomerase and inducing redox stress that triggers non‐apoptotic ...
Vo Quang Huy Phan, Jo’ Del Gobbo, Mukundam Vanga, Deepika V. Karade, Cristina Marzano, Valentina Gandin, Laura Rigon, Carlo Santini, Maura Pellei, H. V. Rasika Dias   +9 more
wiley   +1 more source

Enhanced delivery of camptothecin to colorectal carcinoma using a tumor-penetrating peptide targeting p32. [PDF]

Acta Biomater
Jiang Y, Wang Z, Li W, Ma T, Li M, Wu S, Lin E, Flader KE, Ma M, Chang M, Li H, Wang W, Lu J.   +12 more
europepmc   +1 more source

Pharmacokinetic Drug–Drug Interaction Potential of Oral Anticancer Drugs

Clinical Pharmacology &Therapeutics, EarlyView.
Drug–drug interaction (DDI) management is critical for safe and effective use of oral anticancer drugs (OADs). Our study objectives were to (i) compile clinically relevant pharmacokinetic (PK) DDI mechanisms for OADs and (ii) assess the prevalence of PK potential DDIs (PDDIs) in patients with advanced solid cancers.
Fatimah Alhurayri, Islam R. Younis, Shadia I. Jalal, Theodore F. Logan, Rohan Maniar, Steven M. Bray, Sara K. Quinney, Zeruesenay Desta, Todd C. Skaar, James E. Tisdale, Tyler Shugg   +10 more
wiley   +1 more source