Results 211 to 220 of about 1,207,383 (287)

Quercetin‐zinc coordination polymer coated CaCO3 nanoparticles potentiate radiotherapy through reprogramming tumor immunosuppression

BMEMat, EarlyView.
Synthesis of QZCaCO3‐PEG to synergistically enhance the immunogenicity of radiotherapy through concurrent Zn2+‐induced cancer cell pyroptosis and Que‐mediated hypoxia amelioration through sequentially suppressing TGF‐β secretion and ECM deposition. Abstract Radiotherapy has demonstrated broad applications in treating solid tumors, but the hostile tumor
Chunjie Wang, Hengze Ding, Yu Hao, Honglin An, Ziliang Dong, Minming Chen, Yujie Zhu, Quguang Li, Bin Huang, Liangzhu Feng   +9 more
wiley   +1 more source

Perioperative dynamics of the prognostic nutritional index predict recurrence and survival after resection for colorectal liver metastases. [PDF]

Medicine (Baltimore)
Tatsuta K, Sakata M, Iwase Y, Takagi T, Matsumoto A, Ida S, Sugiyama K, Kojima T, Akai T, Torii K, Furuhashi S, Shimizu M, Takeda M, Morita Y, Kikuchi H, Hiramatsu Y, Kurachi K, Takeuchi H.   +17 more
europepmc   +1 more source

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source

Robust multicentre detection and classification of colorectal liver metastases on CT: application of foundation models. [PDF]

NPJ Precis Oncol
Mali SA, Salahuddin Z, Zhang Y, Aichert A, Zhong X, Woodruff HC, Bobowicz M, Riklund K, Kupčinskas J, Faggioni L, Francischello R, Miclea RL, Lambin P, EUCanImage working group.   +13 more
europepmc   +1 more source

From pathogen to “living drug factory” innovative strategies and clinical translation of bacteria as programmable intelligent vectors for cancer therapy

BMEMat, EarlyView.
Engineered bacteria serve as smart, living therapeutics that target tumors, deliver drugs, and remodel immunosuppressive microenvironments. This review highlights their potential to potentiate immunotherapy, radiotherapy, and chemotherapy, offering a promising paradigm for precise and synergistic cancer treatment. Abstract The dynamic interplay between
Haonan Shen, Weichen Zhang, Gaoli Niu, Li Wang, Ruiyan Li, Yueyue Fan, Feixue Lu, Lingling Xu, Xiaoyuan Ji, Yong Kang   +9 more
wiley   +1 more source

Clinical Advances in Hepatobiliary Surgery: Diagnosis, Prognosis, Management and Surgery for Colorectal Liver Metastases. [PDF]

J Clin Med
E Giakoustidis A, N Papadopoulos V, E Giakoustidis D, Donadon M, Torzilli G.   +4 more
europepmc   +1 more source

Turning Bonding Into Function: The Emerging Role of the Bioactive Selenium─Metal Motif in Toxicology and Medicinal Chemistry

Chemistry – A European Journal, EarlyView.
Balancing Act: Se─M bond serving as the fulcrum of the balance scale to compare the different weight of toxicity and therapeutic effects in biological environment. ABSTRACT The synthesis and characterization of organo‐selenium compounds have attracted considerable interest for decades, driven by the search for efficient catalysts and bioinspired ...
Matteo Filippi, Alessandro Rubbi, Pablo A. Nogara, Giovanni Ribaudo, Vito Lippolis, João B. T. Rocha, Laura Orian   +6 more
wiley   +1 more source

Impact of an AI prognostic tool on clinician performance in colorectal liver metastases. [PDF]

NPJ Digit Med
Chen Q, Tong J, Deng Y, Bi X, Li Y, Li K, Zhao H.   +6 more
europepmc   +1 more source

Association of Urinary pH With Overall Survival in Patients With Stage IV Cancer: A Single‐Center Retrospective Cohort Study

Cancer Nexus, EarlyView.
ABSTRACT Objective This single‐center retrospective cohort study evaluated whether, among patients with stage IV cancer who participated in a pragmatic “alkalization therapy”—defined as a low potential renal acid load diet plus oral sodium bicarbonate and/or potassium/sodium citrate—urinary pH was associated with long‐term survival.
Shion Kachi, Kazuyuki Suzuki, Reo Hamaguchi, Ryoko Narui, Hiromasa Morikawa, Hiromi Wada   +5 more
wiley   +1 more source

Explainable Boosting Machine Predicting Length of Stay After Liver Surgery in Patients with Colorectal Liver Metastases. [PDF]

Cancers (Basel)
Knøfler LA, Millarch AS, Møller SP, Klubien J, Flak RV, Fristrup CW, Hillingsø JG, Nielsen SD, Sillesen M, Smith HG, Pommergaard HC.   +10 more
europepmc   +1 more source