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The role of MLH1, MSH2 and MSH6 in the development of colorectal cancer in Uganda. [PDF]

open access: yesBMC Cancer
Wismayer R   +8 more
europepmc   +1 more source
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Loss of p21WAF1/Cip1 protein expression accompanies progression of sporadic colorectal neoplasms but not hereditary nonpolyposis colorectal cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research, 1998
p21 (p21WAF1/Cip1), a cyclin-dependent kinase inhibitor, induces G1 arrest and can inhibit the activity of the proliferating cell nuclear antigen (PCNA). We analyzed p21 expression during colorectal tumorigenesis, its association with its transcriptional regulator p53, and its relationship to rates of cell proliferation and apoptosis.
F A, Sinicrope   +7 more
openaire   +1 more source

Colorectal cancer statistics, 2023

Ca-A Cancer Journal for Clinicians, 2023
Nikita Sandeep Wagle   +2 more
exaly  

Clinical management of metastatic colorectal cancer in the era of precision medicine

Ca-A Cancer Journal for Clinicians, 2022
Fortunato Ciardiello   +2 more
exaly  

Incidence of Hereditary Nonpolyposis Colorectal Cancer and the Feasibility of Molecular Screening for the Disease

New England Journal of Medicine, 1998
Lauri A Aaltonen   +2 more
exaly  

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