Results 111 to 120 of about 366,130 (353)

Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia [PDF]

, 2015
published_or_final_versio
Chiu, PW, Hon, SS, Lee, JF, Leung, WW, Mak, TW, Ng, SS, Wong, CLT   +6 more
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Ahlquist, Allison, Allison, Allison, Allison, Atkin, Barrows, Brenner, Burtonwood, Callum G. Fraser, Center, Cole, Cole, Cole, Cole, Crotta, Denters, Digby, Fleisher, Fletcher, Fraser, Fraser, Fraser, Fraser, Fraser, Graeme P. Young, Grazzini, Halloran, Hardcastle, Hewitson, Hoff, Hol, Imperiale, Imperiale, James E. Allison, Jemal, Jemal, Khalid-de Bakker, Kronborg, Levi, Levi, Levin, Mandel, Morikawa, Niv, Osborn, Park, Petrelli, Potter, Potter, Potter, Potter, Potter, Qaseem, Quintero, Raginel, Robinson, Rozen, Saito, Saito, Schoen, Segnan, Segnan, Shaukat, Shimbo, Simon, Songster, Songster, St John, Steele, Steele, Stegeman, Stephen P. Halloran, Sugerman, Tao, van Roon, van Roon, van Roon, van Rossum, Vart, Vellacott, Ventura, Walsh, Williams, Young, Zajac, Zauber   +86 more
core   +3 more sources

Endoscopic submucosal dissection for colorectal neoplasms

World Journal of Gastrointestinal Endoscopy, 2009
Although endoscopic submucosal dissection (ESD) gains acceptance as one of the standard treatments for esophageal and stomach neoplasms in Japan, it is still in the developing stage for colorectal neoplasms. In terms of indications, little likelihood of nodal metastasis and technical resectability are principally considered.
openaire   +3 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Modifiable factors of development and recurrence of adenomatous colorectal polyps (literature review)

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Relevance. Adenomatous colorectal polyps are associated with a high risk of developing a malignant tumor. They are considered precancerous conditions and can lead to the development of colorectal cancer.
I. G. Gataullin, B. A. Sakhabetdinov, B. R. Valitov, K. N. Ermakova, A. V. Kalyamova   +4 more
doaj   +1 more source

A prospective single centre study comparing computed tomography pneumocolon against colonoscopy in the detection of colorectal neoplasms [PDF]

, 2000
Yin M. Miao, Z. Amin, Jeremiah C. Healy, Paul Burn, N. Murugan, David Westaby, T G Allen-Mersh   +6 more
openalex   +1 more source