Results 41 to 50 of about 272,839 (312)

Effects of perioperative supplementation with omega-3 fatty acids on leukotriene B4 and leukotriene B5 production by stimulated neutrophils in patients with colorectal cancer: a randomized, placebo-controlled intervention trial [PDF]

, 2014
Omega-3 fatty acids (n-3 FA) may have beneficial clinical and immune-modulating effects in surgical patients. In a randomized, double-blind, prospective, placebo-controlled trial, 148 patients referred for elective colorectal cancer surgery received an n-
Schmidt, E.B., Schmidt, Lone, Thorlacius-Ussing, Ole; id_orcid, Thorlacius-Ussing, O., Erik Schmidt, Ole Thorlacius-Ussing, Rasmussen, Henrik Højgaard, Lundbye-Christensen, S., Lindhorff-Larsen, K., Lindorff Larsen, Karen, Sorensen, L.S., Calder, P.C., Henrik Rasmussen, Søren Lundbye-Christensen, Rasmussen, H.H., Lundbye-Christensen, Søren; id_orcid, Lone Sorensen, Philip. Calder, Calder, Philip C, Schmidt, Erik Berg, Karen Lindorff-Larsen   +20 more
core   +1 more source

Epidural analgesia and mortality after colorectal cancer surgery : A retrospective cohort study [PDF]

, 2021
Background: Epidural analgesia (EA) has been the standard of care after major abdominal surgery for many years. This study aimed to correlate EA with postoperative complications, short- and long-term mortality in patients with and without EA after open ...
Forssten, Maximilian Peter, Mohseni, Shahin,, Bass, Gary Alan,, Gupta, Anil,, Hjelmqvist, Hans, Falk, Wiebke, Matthiessen, Peter, Bass, Gary Alan, Falk, Wiebke,, Gupta, Anil, Mohseni, Shahin, Hjelmqvist, Hans,, Forssten, Maximilian Peter,, Matthiessen, Peter,   +13 more
core   +1 more source

Perioperative infection prophylaxis and risk factor impact in colon surgery [PDF]

, 2000
Background: A prospective observational study was undertaken in 2,481 patients undergoing elective colon resection in 114 German centers to identify optimal drug and dosing modalities and risk factors for postoperative infection.
Rau, H. G., Zimmermann, A., Lachmann, A., Kohler, L., Mittelkotter, U., Kullmann, K. H.   +5 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Patients' views on follow up of colorectal cancer: implications for risk communication and decision making [PDF]

, 2003
Background: Medical views about the clinical value and potential detrimental effect on quality of life of postoperative follow up are divided. There is no literature on the views of British patients with colorectal cancer towards the follow up process.
Heyman, Bob, Papagrigoriadis, S., B Heyman, S Papagrigoriadis   +3 more
core   +1 more source

Meta-analysis of laparoscopic anterior resection with natural orifice specimen extraction (NOSE-LAR) versus abdominal incision specimen extraction (AISE-LAR) for sigmoid or rectal tumors

World Journal of Surgical Oncology, 2020
Background Natural orifice specimen extraction surgery is a novel technique of minimally invasive surgery. The purpose of this study was to compare the safety of laparoscopic anterior resection with natural orifice specimen extraction (NOSE-LAR) and ...
Jun He, Hai-Bo Yao, Chang-Jian Wang, Qin-Yan Yang, Jian-Ming Qiu, Jin-Ming Chen, Zhong Shen, Guan-Gen Yang   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The Prognostic Significance of Tumor Deposit Count for Colorectal Cancer Patients after Radical Surgery

Gastroenterology Research and Practice, 2020
Background. The prognostic value of tumor deposit (TD) count in colorectal cancer (CRC) patients has been rarely evaluated. This study is aimed at exploring the prognostic value of TD count and finding out the optimal cutoff point of TD count to ...
Kuo Zheng, Nanxin Zheng, Cheng Xin, Leqi Zhou, Ge Sun, Rongbo Wen, Hang Zhang, Guanyu Yu, Chenguang Bai, Wei Zhang   +9 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Economic evaluation of laparoscopic surgery for colorectal cancer [PDF]

, 2007
Objectives: To assess the cost-effectiveness of laparoscopic surgery compared with open surgery for the treatment of colorectal cancer. Methods: A Markov model was developed to model cost-effectiveness over 25 years.
Aberdeen Health Technology Assessment Group, Hernández, Rodolfo Andrés, Vale, Luke David, De Verteuil, Robyn   +3 more
core   +1 more source