Results 101 to 110 of about 1,247,855 (284)

Intermolecular Carbon–Carbon Naphthalene Coupling Involves a Radical Mechanism Driven by Cytochrome P450 in Alternaria alternata

open access: yesAngewandte Chemie, EarlyView.
1,8‐DHN is an important intermediate to form complex aromatic ring systems. Phenol‐coupling reactions are important for the dimerization of two molecules. Here, we show that a fungal cytochrome P450 enzyme catalyzes specific C─C bonds. ABSTRACT Dihydroxynaphthalene (DHN) derivatives are precursors of biologically important molecules, including melanin ...
Jia Gao   +8 more
wiley   +2 more sources

Spatiotemporally Controlled Sequential Chemo‐Immunotherapy Activates Pyroptosis for Robust Anti‐Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A glutathione and ultrasound dual‐responsive cerasome achieves sequential co‐delivery of gemcitabine and BMS1166 in tumors. Chemotherapy priming followed by on‐demand PD‐L1 blockade synergistically amplifies anti‐tumor immunity, inhibiting primary tumor growth, distant metastasis and inducing durable immune memory.
Suhui Sun   +9 more
wiley   +1 more source

Plant Metabolites Screening Identifies 7‐epi‐10‐Deacetyltaxol Inhibiting Cell Division by Interfering With the Cell Cycle and Microtubule Organization

open access: yesAdvanced Science, EarlyView.
In this study, an efficient screening system is developed for plant metabolites to find a compound, 7‐epi‐10‐deacetyltaxol, inhibits tissue elongation. It suppresses plant growth through brassinosteroid and microtubule pathways. It is later applied to animal cells and human tumor organoids, resulting in similar cell division suppression. These findings
Yan‐Jie Zhang   +20 more
wiley   +1 more source

Dual Transitions Petri Net based Modelling Technique for Embedded Systems Specification

open access: yes, 2001
This paper presents a new modelling technique capable of modelling both control and data information using a single unified approach. This is achieved by modifying the classical Petri Net structure, allowing it to have two types of transitions and arcs ...
Varea, Mauricio, Al-Hashimi, Bashir M.
core   +1 more source

An Emergency Response Framework Design and Performance Analysis for Ship Fire Incidents in Waterway Tunnels

open access: yesFire
Waterway tunnels, a novel type of infrastructure designed for inland waterways in mountainous gorge regions, have seen rapid development in recent years.
Jian Deng, Shaoyong Liu, Xiaohan Zeng
doaj   +1 more source

Wetting‐Driven Transfer of Flexible Ultra‐Thin Temperature Sensors

open access: yesAdvanced Electronic Materials, EarlyView.
A wetting‐driven transfer approach enables ultra‐thin temperature sensors to be transferred from a super‐hydrophilic donor substrate onto rigid, curved, and biological receiver substrates. By combining controlled wetting with a conformal Parylene carrier layer, the method preserves stable thermal sensing performance while expanding the integration of ...
Hafiza Faiqa Maqsood   +5 more
wiley   +1 more source

A Computational Approach for Biomimetic Design of Liver‐On‐A‐Chip

open access: yesAdvanced Intelligent Discovery, EarlyView.
A biomimetic liver‐on‐a‐chip with antiparallel perfusion was designed using COMSOL‐guided simulation to replicate hepatic acinus transport. Full‐scale modelling revealed diffusion‐dominated, length‐dependent nutrient gradients and low‐shear conditions.
Zhenxu Yang   +9 more
wiley   +1 more source

Formal Modeling and Verification for MVB

open access: yesJournal of Applied Mathematics, 2013
Multifunction Vehicle Bus (MVB) is a critical component in the Train Communication Network (TCN), which is widely used in most of the modern train techniques of the transportation system.
Mo Xia   +3 more
doaj   +1 more source

A novel fault detection and diagnostic Petri net methodology for dynamic systems [PDF]

open access: yes
Faults can have significant, negative impacts on the operation and performance of simple and complex dynamic systems. Based on the integration of Bayesian network diagnostic features with Petri net formalism, the existing Bayesian-supported Petri net ...
Remenyte-Prescott, Rasa   +2 more
core   +1 more source

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao   +5 more
wiley   +1 more source

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