Results 61 to 70 of about 167,532 (264)
Resolving Heterogeneity of Targeted Lipid Nanoparticles Through Solution‐Based Biophysical Analyses
Advanced Materials, EarlyView.AF4‐UV‐DLS‐MALS‐SAXS resolves previously inaccessible targeted lipid nanoparticle (tLNP) subpopulations that differ in size, shape, and composition. Correlation of subpopulation‐resolved biophysical properties with in vivo RNA delivery reveals that targeted placental transfection is associated with distinct tLNP subpopulations rather than ensemble ...
Hannah C. Geisler +14 more
wiley +1 more source
Recent Advances in Ferrite‐Based Materials for Biomedical Applications: A Comprehensive Review
Advanced Materials, EarlyView.Ferrite nanoplatforms are presented as tunable biomedical materials in which synthesis control, cation engineering, defect/morphology regulation, and surface functionalization govern structure–property–bioactivity relationships. These design strategies enable multifunctional applications including MRI contrast, magnetic hyperthermia, targeted drug ...
Pramod D. Mhase +6 more
wiley +1 more source
PathogensDengue virus (DENV), an important mosquito-borne orthoflavivirus, represents a growing global threat due to its geographic expansion and recent outbreaks worldwide.
Perla Pérez-Tepos +8 more
doaj +1 more source
True Closed‐Loop Recyclable Hydrogels Enabled by Imine Boronic Ester Crosslinking
Advanced Materials, EarlyView.Subtle molecular differences in imine boronic ester crosslinkers profoundly influence hydrogel properties. 2‐formylphenylboronic acid crosslinkers form previously undisclosed 3‐amino‐benzoxaborole heterocycles, enhancing elasticity despite lower crosslinking density compared to their 4‐formylphenylboronic acid counterparts.
Jenna A. King +5 more
wiley +1 more source
Frontiers in Microbiology, 2018 A simple, sensitive and selective colorimetric biosensor for the detection of Staphylococcal enterotoxin B (SEB) was developed using SEB-binding aptamer (SEB2) as recognition element and unmodified gold nanoparticles (AuNPs) as colorimetric probes.
Bhairab Mondal +4 more
doaj +1 more source
Advanced Materials, EarlyView.A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte +21 more
wiley +1 more source
Advanced Materials, EarlyView.By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang +10 more
wiley +1 more source
AnimalsFeline herpesvirus type 1 (FHV-1) is one of the major pathogens causing upper respiratory tract disease (URTD) in cats, and is widely prevalent among domestic cats and other felids worldwide.
Shushuai Yi +7 more
doaj +1 more source
At Home Detection of Ovarian Health Biomarker in Menstruation Blood
Advanced Materials Technologies, EarlyView.A lateral flow assay enables the detection of anti‐Müllerian hormone directly in unprocessed menstrual blood using silica‐gold nanoshells and smartphone‐assisted machine learning analysis. The platform supports decentralized, user‐operated testing in wearable and dipstick formats, highlighting the potential of menstrual blood as a non‐invasive matrix ...
Lucas Dosnon +3 more
wiley +1 more source
Sensing and Bio-Sensing Research, 2019 In this paper, a label-free aptamer-based colorimetric assay was developed by incorporating catalytic Au nanoparticles/Graphene (Au NPs/Gr) nanohybrids. As an efficient peroxidase mimic, Au NPs/Gr can oxidize ABTS11 2,2′-azino-bis (3-ethylbenzothiazoline-
Junping Tian
doaj +1 more source