Results 71 to 80 of about 231,641 (313)

Nanomaterials for Healthcare Biosensing Applications [PDF]

, 2019
In recent years, an increasing number of nanomaterials have been explored for their applications in biomedical diagnostics, making their applications in healthcare biosensing a rapidly evolving field.
Altintas, Zeynep, Pirzada, Muqsit
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

A Compact Detection Platform Based on Gradient Guided-Mode Resonance for Colorimetric and Fluorescence Liquid Assay Detection

Sensors, 2021
This paper presents a compact spectral detection system for common fluorescent and colorimetric assays. This system includes a gradient grating period guided-mode resonance (GGP-GMR) filter and charge-coupled device.
Jing-Jhong Gao, Ching-Wei Chiu, Kuo-Hsing Wen, Cheng-Sheng Huang   +3 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Recent Advances in Nanomaterials for Enhanced Colorimetric Detection of Viruses and Bacteria

Chemosensors
The increasing prevalence of pathogen outbreaks underscores the urgent need for rapid, accurate, and cost-effective diagnostic tools. Colorimetric detection has gained significant attention among the available techniques due to its simplicity ...
Caroline R. Basso, Marcos V. B. Filho, Victoria D. Gavioli, Joao P. R. L. L. Parra, Gustavo R. Castro, Valber A. Pedrosa   +5 more
doaj   +1 more source

Development of Optical Biosensor Technologies for Cardiac Troponin Recognition [PDF]

, 2015
Acute myocardial infarction (AMI) is the leading cause of death among cardiovascular diseases. Among the numerous attempts to develop coronary marker concepts into clinical strategies, cardiac troponin is known as a specific marker for coronary events ...
Abdolrahim, Mojgan, Alhosseini, Sanaz Naghavi, Rabiee, Mohammad, Tahriri, Mohammadreza, Tayebi, Lobat, Yazdanpanah, Sara   +5 more
core   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

FEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

Design of highly perceptible dual-resonance all-dielectric metasurface colorimetric sensor via deep neural networks

Scientific Reports, 2022
Colorimetric sensing, which provides effective detection of bio-molecular signals with one’s naked eye, is an exceptionally promising sensing technique in that it enables convenient detection and simplification of entire sensing system.
Hyunwoo Son, Sun-Je Kim, Jongwoo Hong, Jangwoon Sung, Byoungho Lee   +4 more
doaj   +1 more source

Tumour cell labelling by magnetic nanoparticles with determination of intracellular iron content and spatial distribution of the intracellular iron [PDF]

, 2013
: Magnetically labelled cells are used for in vivo cell tracking by MRI, used for the clinical translation of cell-base therapies. Studies involving magnetic labelled cells may include separation of labelled cells, targeted delivery and controlled ...
Alexiou, Alexiou, Alfred Cuschieri, Amemiya, Brekke, Buerli, Bulte, Bulte, Corot, Foster, Frank, Frimpong, Furlani, Hong, Hoskins, Huberman, Ivkov, Jiang, Kamau, Lee, Lewin, Liu, Matuszewski, Mykhaylyk, Oudkerk, Park, Pinkse, Prentice, Riemer, Shen, Sun, Sykova, Thorek, Walczak, Wang, Wang, Wu, Zhang, Zhang, Zhang, Zhigang Wang, Zhu   +41 more
core   +5 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source