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An In Situ Study on Nanozyme Performance to Optimize Nanozyme-Strip for Aβ Detection
The nanozyme-strip is a novel POCT technology which is different from the conventional colloidal gold strip. It primarily utilizes the catalytic activity of nanozyme to achieve a high-sensitivity detection of target by amplifying the detection signal ...
Yaying Luo +6 more
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Antimicrobial Nanozymes: Structure–Activity-Guided Design, Synergy, and Applications [PDF]
Nanozymes are emerging as versatile antimicrobial agents to tackle drug-resistant infections and biofilm-associated persistence. In this review, we present an integrated framework that links natural enzyme-mediated host defense to the rational ...
Yuan Liu +8 more
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Cu2O@CeO2 heterostructure nanozyme with synergistic amplification effect-enhanced immunoassay for sensitive detection of Salmonella in food [PDF]
Colorimetric immunoassays based on nanozyme labelling offer promising solution to rapid detect pathogenic bacteria for ensuring food safety. However, sluggish electron transfer kinetics and finite active sites of nanozyme result in unsatisfactory ...
Ruya Guo +8 more
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Catalytic lactate-regulatory nanosystems attenuate cellular senescence for atherosclerosis amelioration [PDF]
Endothelial senescence is a pivotal driver in the pathogenesis of atherosclerosis (AS), a process accompanied by metabolic reprogramming and increased lactate (LA) production. The accumulated LA stimulates reactive oxygen species (ROS) generation and the
Chang Wang +7 more
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As artificial substitutes for natural enzymes, nanozymes possess advantages such as high catalytic activity, low cost, excellent stability, and suitability for large‐scale production.
Caixia Zhu +4 more
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Nanozymes—Hitting the Biosensing “Target” [PDF]
Nanozymes are a class of artificial enzymes that have dimensions in the nanometer range and can be composed of simple metal and metal oxide nanoparticles, metal nanoclusters, dots (both quantum and carbon), nanotubes, nanowires, or multiple metal-organic frameworks (MOFs).
Yingfen Wu +2 more
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Nanozybiotics: Nanozyme-Based Antibacterials against Bacterial Resistance
Infectious diseases caused by bacteria represent a global threat to human health. However, due to the abuse of antibiotics, drug-resistant bacteria have evolved rapidly and led to the failure of antibiotics treatment. Alternative antimicrobial strategies
Caiyu Zhou +3 more
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Nanozymes as Enzyme Inhibitors
Nanozyme is a type of nanomaterial with intrinsic enzyme-like activity. Following the discovery of nanozymes in 2007, nanozyme technology has become an emerging field bridging nanotechnology and biology, attracting research from multi-disciplinary areas focused on the design and synthesis of catalytically active nanozymes.
Huang,Yaling +4 more
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Nanozymes in Tumor Theranostics
Nanozymes, a new generation of enzyme mimics, have recently attracted great attention. Nanozymes could catalyze chemical reactions as biological enzymes under physiologically mild conditions with higher-efficiency catalytic activities. Moreover, nanozymes could overcome the shortcomings of natural enzymes, such as easy inactivation, high cost, and low ...
Qiulian Ma +5 more
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Over the past 15 years, many articles have considered "nanozymes" as ferromagnetic nanoparticles having an "intrinsic peroxidase-like activity" in the presence of hydrogen peroxide. However, the definition and the catalytic activity of these nanozymes have been questioned. The present Perspective reports the main criteria that are essential to classify
Robert, Anne, Meunier, Bernard
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