Results 91 to 100 of about 61,204 (302)

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

An artificial intelligence-assisted microfluidic colorimetric wearable sensor system for monitoring of key tear biomarkers

npj Flexible Electronics
The precise, simultaneous, and rapid detection of essential biomarkers in human tears is imperative for monitoring both ocular and systemic health. The utilization of a wearable colorimetric biochemical sensor exhibits potential in achieving swift and ...
Zihu Wang, Yan Dong, Xiaoxiao Sui, Xingyan Shao, Kangshuai Li, Hao Zhang, Zhenyuan Xu, Dongzhi Zhang   +7 more
doaj   +1 more source

Evidence that the degree of band 3 phosphorylation modulates human erythrocytes nitric oxide efflux – in vitro model of hyperfibrinogenemia [PDF]

, 2011
© 2011 – IOS Press and the authors. All rights reservedRecent evidence has shown that plasma fibrinogen, a major cardiovascular risk factor, interacts with the erythrocyte membrane and acts to influence blood flow via erythrocyte nitric oxide (NO ...
Almeida, J. P. Lopes de, Freitas-Santos, T., Saldanha, C.   +2 more
core   +1 more source

From Food to Power: Hydrogel Thermoelectrics for Ingestible Electronics

Advanced Functional Materials, EarlyView.
We introduce a fully edible thermoelectric–electrochromic platform that harvests heat from food and converts it into a visible color change. N‐type and p‐type hydrogel thermoelectric generators connected in series power anthocyanin‐based electrochromic displays, demonstrating the feasibility of safe, biodegradable, ingestible systems for on‐food ...
Antonia Georgopoulou, Bokeon Kwak, Dario Floreano, Esther Amstad   +3 more
wiley   +1 more source

Distributed environmental monitoring [PDF]

, 2013
With increasingly ubiquitous use of web-based technologies in society today, autonomous sensor networks represent the future in large-scale information acquisition for applications ranging from environmental monitoring to in vivo sensing.
Cleary, John, Collins, Fiachra, Diamond, Dermot, Fay, Cormac, Zuliani, Claudio   +4 more
core  

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

Video analysis of events within chemical sensor networks [PDF]

, 2005
This paper describes how we deploy video surveillance techniques to monitor the activities within a sensor network in order to detect environmental events.
Beirne, Stephen, Cooke, Eddie, Corcoran, Brian, Diamond, Dermot, O'Connor, Noel E., Shepherd, Roderick, Smeaton, Alan F.   +6 more
core  

Photo-responsive polymeric structures based on spiropyran [PDF]

, 2012
Spiropyrans are one of the most popular classes of photochromic compounds that change their optical and structural properties in response to external inputs such as light, protons and metal ions, making them ideal molecules for the fabrication of ...
Adelmann, Alonso, Anastasiadis, Angiolini, Bardavid, Bassetti, Beebe, Beiermann, Beiermann, Bell, Benito-Lopez, Benito-Lopez, Berkovic, Byrne, Byrne, Byrne, Byrne, Byrne, Cheng, Chung, Coleman, Coleman, Connal, Darwish, Dattilo, Davis, Delaire, Dong, Doron, Dürr, Fischer, Florea, Florea, Fries, Fries, Fries, Garcia, Guo, Higuchi, Hirshberg, Imai, Irie, Ivanov, Joseph, Kimura, Kobayashi, Kotharangannagari, Kwon, LaVan, Lee, Lee, Lee, Lee, Levy, Li, Lin, Lygeraki, Minkin, Natali, O'Bryan, Park, Park, Pennakalathil, Piech, Radu, Richter, Rosario, Rosario, Sakai, Samanta, Samoladas, Saragi, Satoh, Shiraishi, Shiraishi, Stauffer, Stitzel, Such, Sugiura, Suzuki, Tachibana, Wang, Zhao   +82 more
core   +2 more sources

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Voltage‐Gated Dedoping of n‐Doped Poly(benzodifurandione) as an Interfacial Protective Mechanism in Electrochromic Devices

Advanced Functional Materials, EarlyView.
Electrochromic polymer stability under overpotential is improved by inserting an ultrathin, transparent n‐doped poly(benzodifurandione) interlayer between indium tin oxide and a poly(3,4‐propylenedioxythiophene)‐based electrochromic polymer. The interlayer supports rapid switching at operating bias, then becomes resistive near +0.8 V to suppress excess
Priyanka Rout, Palak Mehra, Won‐June Lee, Liyan You, Jianguo Mei   +4 more
wiley   +1 more source