Results 41 to 50 of about 52,075 (266)

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Colorimetry technique for scalable characterization of suspended graphene

open access: yes, 2016
Previous statistical studies on the mechanical properties of chemical-vapor-deposited (CVD) suspended graphene membranes have been performed by means of measuring individual devices or with techniques that affect the material.
Cartamil-Bueno, Santiago J.   +5 more
core   +5 more sources

Paper-Based Analytical Device for Zinc Ion Quantification in Water Samples with Power-Free Analyte Concentration

open access: yesMicromachines, 2017
Insufficient sensitivity is a general issue of colorimetric paper-based analytical devices (PADs) for trace analyte detection, such as metal ions, in environmental water.
Hiroko Kudo   +4 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

The botany and proximate analyses of some edible species of the New Zealand flora : a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in Plant Biology at Massey University [PDF]

open access: yes, 1993
1. The edible organs of some New Zealand plant species have been assessed at light microscope level for their botanical basis, and for their nutritional basis by proximate analysis and Plasma Emission Spectrometry. 2.
Elliot, Rose
core  

Variação intraespecífica da cor da pelagem de uma espécie de pequeno roedor sul-americano [PDF]

open access: yes, 2016
Intra-specific color variation is often underestimated by researchers, and among mammalian species, intra-specific differences in coloration are poorly documented for most species.
Barquez, Ruben Marcos   +3 more
core   +2 more sources

Extracting Target Components from Fresh and Refined Sac Roe: Kinetic Patterns

open access: yesТехника и технология пищевых производств
Sac roe makes up 20% of all industrial fish waste. Due to its high nutritional and biological value, sac roe can be recycled into protein concentrates and fractionated lecithin.
Zarema M. Arabova   +4 more
doaj   +1 more source

Influence of interventional nonsurgical periodontal treatment on levels of salivary and serum nitric oxide in smokers and nonsmokers with chronic periodontitis

open access: yesJournal of Indian Society of Periodontology, 2016
Background and Objective: Nitric oxide (NO) is a widespread signaling molecule which is known to influence varied biological processes. However, an uncontrolled high level of NO accelerates tissue destruction.
Pooja Purushottam Wattamwar   +3 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Apparatus enables automatic microanalysis of body fluids [PDF]

open access: yes, 1966
Apparatus will automatically and quantitatively determine body fluid constituents which are amenable to analysis by fluorometry or colorimetry. The results of the tests are displayed as percentages of full scale deflection on a strip-chart recorder.
Soffen, G. A., Stuart, J. L.
core   +1 more source

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