Results 151 to 160 of about 238,036 (301)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Harlequin colour change

, 2017
Harlequin colour change (HCC) is a rare, benign and transient colour change presenting in normal healthy neonates in initial days of life and resolves spontaneously.
Yezdan, Mohammad Ali, Khemani, Suneeta, Karim, Sarfaraz, Bahadur Ali, Shirin   +3 more
core  

Methods and Workflows for Colour Change Modelling and Reconstruction

156This chapter presents end-to-end methodologies and workflows for modelling, reconstructing, and communicating colour change in cultural heritage across four scenarios: classical sculpture, paintings, historical textiles, and early colour photographs ...
Selka, Faïçal, Sotiropoulou, Sophia, Buti, David, Siozos, Panagiotis, Arteaga, Yoko, Hardeberg, Jon Yngve, Sinha, Saptarshi Neil, Sandu, Irina Crina Anca, Langford, Catlin, Monico, Letizia, Pinto, Catarina, Barandoni, Cristiana, Doherty, Brenda, Burgio, Lucia, Ciortan, Irina-Mihaela, Magrini, Donata, Trumpy, Giorgio   +16 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Effect of temperature fluctuation on colour change and softening of postharvest sweet cherry. [PDF]

RSC Adv, 2021
Xin Y, Liu Z, Zhang Y, Shi X, Chen F, Liu K.   +5 more
europepmc   +1 more source

Harlequin Colour Change.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2018
Harlequin colour change (HCC) is a rare, benign and transient colour change presenting in normal healthy neonates in initial days of life and resolves spontaneously. It is thought to be due to hypothalamic immaturity, leading to capillary bed dysregulation. Gravity might also play a role, as this is apparent on the dependent side.
Suneeta, Khemani, Shirin Bahadur, Ali, Sarfaraz, Karim, Mohammad Ali, Yezdan   +3 more
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Light source classification and colour change modelling for understanding and predicting pigments discolouration

JPhys Photonics
In this study, we introduce a simple but effective model, combined with a classification system for light sources based on their spectral profile approximated by the relative power distribution in the red, green and blue regions, which successfully fits ...
Panagiotis Siozos, Letizia Monico, Aldo Romani, Costanza Miliani, Brenda Doherty, Irina Crina Anca Sandu, Hartmut Kutzke, Ingrid M T Flåte, Petros Stavroulakis, Sophia Sotiropoulou   +9 more
doaj   +1 more source

Changing Colours of Autumn

CHIMIA, 2023
Changes in the dominant pigments in leaves of deciduous trees lead to beautiful autumnal hues. However, physiological and ecological reasons for the colours are still open for debate.
openaire   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source