Results 141 to 150 of about 238,036 (301)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

How does insect visitation trigger floral colour change?

open access: yes, 2003
1. Visitation by the key pollinator, Bombus terrestris , was implicated in inducible flower colour change in Lupinus pilosus . Behaviour at the flower and rate of visitation by these bumble bees had specific effects; exclusion of this flower visitor led ...
Nuttman, CV, Willmer, Patricia Gillian
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Human Visual Perception and Spatial Models of Colour

open access: yes, 2007
Colour can deeply change its characteristics when put and analyzed into its spatial context. A growing family of algorithms treat/modify/enhance colour information in its visual context, also known as spatial colour methods.
A. Rizzi
core  

Biomimetic Surface Modification of Dental Zirconia via UV Irradiation for Enhanced Aesthetics and Wettability

open access: yesBiomimetics
Zirconia is a material that mimics human teeth and has been extensively studied and applied. This study investigated the surface modifications of dental zirconia induced by two UV-C wavelengths (222 and 254 nm).
Fengdan Pan   +7 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Flap-necked chameleons change colour to match their background [PDF]

open access: yes
Popular culture leads us to believe that chameleons change colour to match their backgrounds, yet surprisingly, this ability has rarely been demonstrated under controlled conditions. Existing research shows that colour change is primarily used for social
Troscianko, J.   +5 more
core   +1 more source

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