Results 61 to 70 of about 15,447 (214)

Pediatric Lichen Sclerosus and Non‐Accidental Trauma: A Systematic Review of Distinguishing Features and Co‐Occurrence

Pediatric Dermatology, EarlyView.
ABSTRACT Background/Objectives Lichen sclerosus (LS) is a chronic autoimmune inflammatory skin disease predominantly affecting the anogenital area that can be mistaken for non‐accidental trauma (NAT) in pediatric patients, such as sexual abuse. Such misdiagnoses can be distressing for families.
Bianca Te, Drue Julien, Kristie Mar, Rebecca Liu, Carly Kirshen   +4 more
wiley   +1 more source

Sustained impact of bivalent HPV immunisation on CIN incidence over two rounds of cervical screening

International Journal of Cancer, Volume 158, Issue 5, Page 1348-1360, 1 March 2026.
What's New? While vaccination against high‐risk HPV infection, the primary cause of cervical malignancy, has demonstrated long‐term effectiveness in clinical trials, real‐life longitudinal data are lacking. Here, the authors present linked long‐term screening data on the effectiveness of bivalent HPV vaccination with a minimum follow‐up of 54 months ...
Timothy J. Palmer, Kimberley Kavanagh, Kate Cuschieri, Ross L. Cameron, Catriona Graham, Allan Wilson, Kirsty Roy   +6 more
wiley   +1 more source

A prospective study of vaginal topical pretreatment of compound sea-buckthorn oil suppository in postmenopausal women prior to colposcopy

Scientific Reports
Postmenopausal women are faced with difficulties in colposcopy, such as easy bleeding from epithelial atrophy, and thinning, atypical colposcopy images, unsatisfactory exposure, and decreased sensitivity of colposcopy. We aimed to improve the sensitivity
Yi Yu, Qing Li, Yuankui Cao, Hongwei Zhang, Yu Song, Qing Cong, Long Sui, Limei Chen   +7 more
doaj   +1 more source

Colposcopic and Histopathologic Comparative Interpretations Among Patients Undergoing Evaluation for Cervical Dysplasia in Western Kenya

European Medical Journal Reproductive Health
Objective: To determine the correlation between colposcopic and final histopathologic results amongst patients undergoing a colposcopic evaluation in cervical dysplasia clinics in Western Kenya. Methods: This was a cross-sectional study, conducted among
Mohamed Ali Hassan, Peter Itsura, Benjamin Elly Odongo   +2 more
doaj   +1 more source

Under which realistic circumstances is hrHPV self‐sampling increasing cervical screening effectiveness in a partly vaccinated population? A modelling study

International Journal of Cancer, Volume 158, Issue 5, Page 1361-1369, 1 March 2026.
What's New? Offering the option of self‐sampling in cervical cancer screening programs could increase participation. However, it could also prompt participants to switch from clinician‐collecting sampling, which has demonstrated higher testing sensitivity and lower loss to follow‐up.
Sylvia Kaljouw, Erik E. L. Jansen, Ellen M. G. Olthof, Jan A. C. Hontelez, Inge M. C. M. de Kok   +4 more
wiley   +1 more source

Long‐term human papillomavirus genotype‐specific risk of cervical high‐grade intraepithelial lesion and cancer—By age group and triage cytology

International Journal of Cancer, Volume 158, Issue 4, Page 931-941, 15 February 2026.
What's new? Human papillomavirus (HPV) testing has revolutionized cervical cancer screening. Nonetheless, its optimal use for distinguishing between high‐ and low‐risk infections to leverage screening benefits remains to be established. Here, long‐term HPV genotype‐specific risk of precancerous cervical intraepithelial neoplasia grade 2 or higher was ...
Maija Vahteristo, Sirpa Heinävaara, Joakim Dillner, Ilkka Kalliala, Pekka Nieminen, Tytti Sarkeala, Maarit K. Leinonen   +6 more
wiley   +1 more source

Enhanced diagnostic accuracy of high‐grade cervical intraepithelial neoplasia in postmenopausal women through PAX1/JAM3 methylation analysis

International Journal of Cancer, Volume 158, Issue 4, Page 1116-1125, 15 February 2026.
What's new? Cervical cancer screening is challenging in postmenopausal women, partly due to physiological changes that reduce the sensitivity of cytology and colposcopy. This study evaluated the diagnostic performance of combined PAX1 and JAM3 gene methylation testing in a large cohort of postmenopausal women undergoing colposcopy. Compared to cytology
Huanzi Peng, Jing Li, Qun Zhou, Hui Zhou, Jiaqi Peng, Jing Wang, Pei Liu, Kun He, Wene Liu, Ping Tan, Lei Li, Xiaobing Xie   +11 more
wiley   +1 more source

Concordance of Colposcopy-Directed Biopsy and Conization Results in Cervical Dysplasia

Gynecology Obstetrics & Reproductive Medicine
OBJECTIVE: Cervical cancer prevention requires proper management of women with cervical intraepithelial neoplasia (CIN). A colposcopy is key to diagnosing CIN in women with abnormal cytology.
Cemre Alan, Ulfet Sena Metin, Ali Acar
doaj   +1 more source

“Atypical Glandular Cells” on Cervical Cytology: Correlation Between Glandular Cell Component Volume and Histological Follow‐Up

Diagnostic Cytopathology, Volume 54, Issue 2, Page 71-77, February 2026.
ABSTRACT Background Atypical glandular cells (AGC) in cervical cytology, as defined by the Bethesda System, indicate nuclear atypia beyond reactive changes but without definitive features of malignancy. Although clinically significant because it prompts follow‐up procedures, no quantitative threshold exists for AGC diagnosis.
Havva Gokce Terzioglu, Alessa Aragao, Julieta E. Barroeta   +2 more
wiley   +1 more source

Predictive biomarkers for regression in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2: A prospective multicenter study in Italy

International Journal of Cancer, Volume 158, Issue 3, Page 587-596, 1 February 2026.
What's new? Cervical intraepithelial neoplasia grade 2 (CIN2) lesions can spontaneously regress, especially in women aged under 30. Better predictive biomarkers are needed to improve risk stratification for active surveillance. This prospective multicenter cohort study evaluated HPV genotyping, p16/ki67 expression, and FAM19A4/miR124‐2 methylation ...
Helena Frayle, Silvia Gori, Alessio Pagan, Marika Soldà, Cesare Romagnolo, Egle Insacco, Licia Laurino, Mario Matteucci, Giuseppe Sordi, Enrico Busato, Manuel Zorzi, Tiziano Maggino, Annarosa Del Mistro, CIN2 Study Working Group, Annarosa Del Mistro, Helena Frayle, Silvia Gori, Rossana Trevisan, Alessio Pagan, Justyna Wojciechowska, Enrico Busato, Tiziano Maggino, Marika Soldà, Cesare Romagnolo, Licia Laurino, Pamela Zambenedetti, Egle Insacco, Mario Matteucci, Maria Teresa Gervasi, Giuseppe Sordi, Marco Torrazzina, Manuel Zorzi, Daria Minucci   +32 more
wiley   +1 more source