Results 161 to 170 of about 451,802 (301)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Column generation approach for the traveling salesman problem
, 1998 We present a new approach, columnwise formulation and column generation, for solving structured combinatorial optimization problems. Instead of defining classes of valid inequalities as in polyhedral combinatorics, we systematically reformulate the ...
Chang, Hsuliang
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd +118 more
wiley +1 more source
Column Generation with a Primal-Dual Method
, 1997 A simple column generation scheme that employs an interior point method to solve underlying restricted master problems is presented. In contrast with the classical column generation approach where restricted master problems are solved exactly, the method
Jacek Gondzio, Robert Sarkissian
core
Design optimization and clinical prospects of a novel portable split-type negative pressure thoracic drainage device. [PDF]
Front Med (Lausanne)Huang S, Li J, Shen H, Yang Y.
europepmc +1 more source
Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity
Arthritis Care &Research, EarlyView.Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley +1 more source
Accelerating column generation schemes : applications to routing problems
, 2005 Many integer optimization problems of great practical importance are today attacked with column generation. Merits of column generation is that it enables the use of compact and flexible formulations of many complex optimization problems, and that it ...
Westerlund, Andreas,, Madsen, Oli,
core
Hydrocarbon Generation Potential, Paleoenvironmental Conditions, and Organic Matter Enrichment of the Fengcheng Formation Black Shales in the Hala'alat Mountain, NW Junggar Basin: Chemostratigraphic Insights from Well HQ‑6. [PDF]
ACS OmegaLi Z +10 more
europepmc +1 more source