Results 71 to 80 of about 815,609 (326)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Derivation of Emissions From Satellite‐Observed Column Amounts and Its Application to TROPOMI NO2 and CO Observations

Geophysical Research Letters, 2022
A unified framework that connects emissions with satellite‐observed column amounts is derived from first principles. The emission information originates from the inner product of the horizontal wind and the gradient of column amount, which is more ...
Kang Sun
doaj   +1 more source

A new column-generation-based algorithm for VMAT treatment plan optimization [PDF]

Physics in Medicine and Biology, 2012
We study the treatment plan optimization problem for volumetric modulated arc therapy (VMAT). We propose a new column-generation-based algorithm that takes into account bounds on the gantry speed and dose rate, as well as an upper bound on the rate of change of the gantry speed, in addition to MLC constraints.
Peng, Fei, Jia, Xun, Gu, Xuejun, Epelman, Marina A., Romeijn, H. Edwin, Jiang, Steve B.   +5 more
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

An Integrated Transmission Expansion and Sectionalizing-Based Black Start Allocation of BESS Planning Strategy for Enhanced Power Grid Resilience

IEEE Access, 2020
This paper proposes a new comprehensive integrated planning strategy for the resilience enhancement of power system, including determining the transmission expansion and sectionalizing-based optimal black start (BS) resources allocation of battery energy
Fang Yao, Tat Kei Chau, Xinan Zhang, Herbert Ho-Ching Iu, Tyrone Fernando   +4 more
doaj   +1 more source

GPU-based ultra-fast direct aperture optimization for online adaptive radiation therapy

, 2010
Online adaptive radiation therapy (ART) has great promise to significantly reduce normal tissue toxicity and/or improve tumor control through real-time treatment adaptations based on the current patient anatomy.
Bazaraa M, Bentley J, Chunhua Men, Earl M A, Fox C, Gu X, Gu X, Hoberock J Bell N, Kokubo M, Langen K M, Li M, Li Y J, Men C, Men C, Steve B Jiang, Wong J R, Wu C, Wu Q J, Xing M Decaudin P Baogang H Xiaopeng Z, Xun Jia, Yan D, Zhang G W   +21 more
core   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

The Angular Set Covering Problem

IEEE Access
We present an innovative extension of the Set Covering Problem, transitioning from a traditional radial covering to an angular covering structure. The decisions are based on locating the facilities and identifying the directional servers installed in ...
Fredy Barriga-Gallegos, Armin Luer-Villagra, Gabriel Gutierrez-Jarpa   +2 more
doaj   +1 more source

The Greenhouse Gas Climate Change Initiative (GHG-CCI): comparative validation of GHG-CCI SCIAMACHY/ENVISAT and TANSO-FTS/GOSAT CO₂ and CH₄ retrieval algorithm products with measurements from the TCCON [PDF]

, 2014
Column-averaged dry-air mole fractions of carbon dioxide and methane have been retrieved from spectra acquired by the TANSO-FTS (Thermal And Near-infrared Sensor for carbon Observations-Fourier Transform Spectrometer) and SCIAMACHY (Scanning Imaging ...
Aben, I., Blumenstock, T., Boesch, H., Buchwitz, M., Burrows, J. P., Butz, A., De Mazière, M., Deutscher, N. M., Dils, B., Frankenberg, C., Griffith, D., Guerlet, S., Hase, F., Hasekamp, O. P., Heymann, J., Notholt, J., Parker, R., Reuter, M., Schneising, O., Sherlock, V., Sussmann, R., Warneke, T., Wunch, D.   +22 more
core  

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source