Results 81 to 90 of about 815,609 (326)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

A Synchronous Optimization Model for Multiship Shuttle Tanker Fleet Design and Scheduling Considering Hard Time Window Constraint

open access: yesJournal of Advanced Transportation, 2018
A Synchronous Optimization for Multiship Shuttle Tanker Fleet Design and Scheduling is solved in the context of development of floating production storage and offloading device (FPSO).
Zhenfeng Jiang   +2 more
doaj   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

open access: yesArthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy   +9 more
wiley   +1 more source

A Column Generation Algorithm for Choice-Based Network Revenue Management [PDF]

open access: yes, 2008
In the last few years, there has been a trend to enrich traditional revenue management models built upon the independent demand paradigm by accounting for customer choice behavior. This extension involves both modeling and computational challenges.
Bront, Juan Jose Miranda
core  

Prevalence of Systemic Lupus Erythematosus in Australia, 2010–2022: A Population‐Based Study Using Linked National Administrative Health Data

open access: yesArthritis Care &Research, Accepted Article.
Objectives Systemic lupus erythematosus (SLE) is a heterogenous inflammatory condition, with widely varying global prevalence estimates. Frequency of SLE in the general population of Australia has been reported to be notably lower than contemporary estimates in countries such as the US or UK at 19‐39 per 100,000 as opposed to 65‐97 per 100,000.
Lucinda Roper   +7 more
wiley   +1 more source

Acceleration of Lagrangian Method for the Vehicle Routing Problem with Time Windows

open access: yesInternational Journal of Industrial Engineering and Production Research, 2012
The analytic center cutting plane method (ACCPM) is one of successful methods to solve nondifferentiable optimization problems. In this paper ACCPM is used for the first time in the vehicle routing problem with time windows (VRPTW) to accelerate ...
Hadi Karimi, Abbas Seifi
doaj  

A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems

open access: yesInternational Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.
A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam   +2 more
wiley   +1 more source

Nanoindentation Criteria for Combinatorial Thin Film Libraries

open access: yesAdvanced Engineering Materials, EarlyView.
Thin‐film material libraries are compositional spreads used for screening composition‐structure‐property relationships. Nanoindentation is often used to characterize mechanical behavior across these systems, however variations in methodology are widespread.
Andre Bohn, Adie Alwen, Andrea M. Hodge
wiley   +1 more source

Temperature and Polarization CMB Maps from Primordial non-Gaussianities of the Local Type

open access: yes, 2007
The forthcoming Planck experiment will provide high sensitivity polarization measurements that will allow us to further tighten the f_NL bounds from the temperature data.
Hansen, Frode K.   +5 more
core   +1 more source

Unleashing the Power of Machine Learning in Nanomedicine Formulation Development

open access: yesAdvanced Functional Materials, EarlyView.
A random forest machine learning model is able to make predictions on nanoparticle attributes of different nanomedicines (i.e. lipid nanoparticles, liposomes, or PLGA nanoparticles) based on microfluidic formulation parameters. Machine learning models are based on a database of nanoparticle formulations, and models are able to generate unique solutions
Thomas L. Moore   +7 more
wiley   +1 more source

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