Results 31 to 40 of about 1,934 (272)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Further insight into an unnamed, medium-sized crouzeliid pliopithecoid from the Vallès-Penedès Basin (NE Iberian Peninsula)

open access: yesSwiss Journal of Palaeontology
Pliopithecoids are a clade of stem catarrhines represented by multiple Middle to Late Miocene genera in the Vallès-Penedès Basin (NE Iberian Peninsula).
Florian Bouchet   +4 more
doaj   +1 more source

Ruminant inner ear shape records 35 million years of neutral evolution

open access: yesNature Communications, 2022
Extrinsic and intrinsic factors impact diversity. On deep-time scales, the extrinsic impact of climate and geology are crucial, but poorly understood.
Bastien Mennecart   +16 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Modelització de terraplens sobre sòls argilosos reforçats amb columnes de graves [PDF]

open access: yes, 2017
Anàlisi del la modelització dels terraplens sobre sòls argilosos reforçats amb columnes de graves per la obtenció d'un model on la discretització de les columnes de graves pugui ser substituïda per un àrea equivalent.
Rofes Ruiz, Jordi
core   +1 more source

The agony column [PDF]

open access: yesCurrent Biology, 1996
If you have a problem, no matter how large or small, Current Biology's ‘agony aunt’ Amber can help.Dear Amber, I have a phobia about scientific meetings. I am invited to speak at many meetings, but can never persuade myself to go. Something about the idea of spending three or four days trying to be civil to complete strangers terrifies me. Can you help?
openaire   +5 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

The Chairman’s column

open access: yesTelecommunications Journal of Australia, 2007
Abstract not available.
openaire   +2 more sources

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