Results 91 to 100 of about 264,751 (352)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Mindsight: Diagnostics in Disorders of Consciousness

Critical Care Research and Practice, 2012
Diagnosis of patients with disorders of consciousness (comprising coma, vegetative state/unresponsive wakefulness syndrome, and minimally conscious state) has long been dependent on unstandardized behavioral tests.
P. Guldenmund, J. Stender, L. Heine, S. Laureys   +3 more
doaj   +1 more source

Exploring the Anti‐Diabetic Potential of Anthocyanins: From Biochemical Pathways to Human Trials

Chronic Diseases and Translational Medicine, EarlyView.
ABSTRACT Diabetes mellitus (DM) is a global health challenge with increasing prevalence rates, particularly in low‐ and middle‐income countries. Anthocyanins (ACs) are potential bioactive compounds found in various fruits and vegetables, attracting the attention of researchers due to their possible role in managing diabetes and its complications ...
Lakshay Panchal, Sangeeta Yadav, Akash Kumar, Tanbeer Kaur, Yashna Bawa, Sarvesh Rustagi, Rahul Mehra   +6 more
wiley   +1 more source

Evaluation of the Therapeutic Potential of Bioactive Materials Based on a Complex of Oxidovanadium(IV) and Exopolysaccharide Levan in a Model of Insulin Resistance in Mice

ChemMedChem, EarlyView.
A low‐toxicity bioactive composition of oxidovanadium(IV) and exopolysaccharide levan is synthesized, characterized, and shown to reduce hyperglycemia, hypertriglyceridemia, and TyG index in a mice model of dexamethasone‐induced insulin resistance. Bioactive compositions containing vanadium complexes have been a viable strategy for constructing more ...
Amanda K. J. P. F. da Silva, Eucilene K. de L. B. Marques, Lidiane M. A. de Lima, Widarlane A. S. Alves, Dayane A. Gomes, Pedro L. Guzzo, Mônica F. Belian, Wagner E. Silva, Eduardo C. Lira   +8 more
wiley   +1 more source

Coma mixedematoso.

Acta Médica Portuguesa, 1992
Five patients, 4 female and 1 male, aged 45 to 73, were observed in myxedema coma between 1984 and 1992. In three patients hypothyroidism was not known. Depressed consciousness, hypothermia, bradycardia and no goiter were common to all and a precipitating factor could be identified in 3 of them.
Fonseca, F, Cortez, L, Guerra, L, Afonso, A, Agapito, A, Malheiro, F, Charneco da Costa, J   +6 more
openaire   +2 more sources

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

Annals of the Child Neurology Society, EarlyView.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf, Timothy M. Crombleholme, Leon G. Epstein, Dawn Gano, Phillip L. Pearl, Timothy V. Salomons, Mark S. Scher, Elise Turk, Klaus‐Peter Zimmer, Harvey B. Sarnat   +9 more
wiley   +1 more source

Measures of CNS-Autonomic Interaction and Responsiveness in Disorder of Consciousness

Frontiers in Neuroscience, 2019
Neuroimaging studies have demonstrated functional interactions between autonomic (ANS) and brain (CNS) structures involved in higher brain functions, including attention and conscious processes.
Francesco Riganello, Francesco Riganello, Stephen Karl Larroque, Carol Di Perri, Carol Di Perri, Valeria Prada, Walter G. Sannita, Steven Laureys   +7 more
doaj   +1 more source

Clinicians' Experiences of Providing Compulsory Care for Youth With Anorexia Nervosa: A Qualitative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective While compulsory treatment is shown to be potentially traumatic for patients, its impact on clinicians has been insufficiently studied. This study aimed to examine clinicians' experiences with providing compulsory nasogastric tube feeding for youth with severe anorexia nervosa, with particular attention to identifying factors ...
T. M. Offringa, R. R. J. M. Vermeiren, C. Bouman, M. C. de Vries, H. G. J. M. Vermetten, P. M. L. Korthals Altes, L. A. Nooteboom   +6 more
wiley   +1 more source

Temperature variability homogenized thermal responses in an ectotherm community along a European longitudinal gradient

Ecography, EarlyView.
Climate change, through rising temperatures, greater variability, and more frequent extremes, is reshaping insect phenology and thermal niches, with profound effects for pest outbreaks. Predicting these impacts requires a clear understanding of species and communities' responses across geographic gradients.
Ruining Li, Chun‐Sen Ma, Léna Jego, Cécile Le Lann, Joan Van Baaren, Gang Ma   +5 more
wiley   +1 more source

Disorders of Consciousness, Language and Communication Following Severe Brain Injury

Psychologica Belgica
Patients with severe brain injuries and disorders of consciousness (DoC) represent a complex clinical population in terms of diagnosis, prognosis, and management, including critical ethical considerations.
Charlène Aubinet, Anaïs Gillet, Amandine Regnier   +2 more
doaj   +1 more source