Results 81 to 90 of about 570,074 (301)

Causes of brain dysfunction in acute coma: a cohort study of 1027 patients in the emergency department [PDF]

, 2019
BACKGROUND: Coma of unknown etiology (CUE) is a major challenge in emergency medicine. CUE is caused by a wide variety of pathologies that require immediate and targeted treatment.
Braun, Mischa, Lindner, Tobias, Lutz, Maximilian, Möckel, Martin, Ploner, Christoph J., Schmidt, Wolf Ulrich   +5 more
core   +1 more source

Coma Stimulation [PDF]

Worldviews on Evidence-based Nursing presents the archives of Online Journal of Knowledge Synthesis for Nursing, 1997
Abstract(1) Coma stimulation is a treatment in which a health care professional or a patient's family member systematically applies stimulation to one or more of the patient's five senses, for the purpose of increasing patient responsiveness. The rationale is that exposure to frequent and various sensory stimulation will facilitate both dendritic ...
openaire   +3 more sources

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Behavioral and electrophysiological effects of network-based frontoparietal tDCS in patients with severe brain injury: A randomized controlled trial

NeuroImage: Clinical, 2020
Background: Transcranial direct current stimulation (tDCS) may promote the recovery of severely brain-injured patients with disorders of consciousness (DOC).
Géraldine Martens, Eleni Kroupi, Yelena Bodien, Gianluca Frasso, Jitka Annen, Helena Cassol, Alice Barra, Charlotte Martial, Olivia Gosseries, Nicolas Lejeune, Aureli Soria-Frisch, Giulio Ruffini, Steven Laureys, Aurore Thibaut   +13 more
doaj   +1 more source

Galaxy Orientations in the Coma Cluster [PDF]

, 2007
We have examined the orientations of early-type galaxies in the Coma cluster to see whether the well-established tendency for brightest cluster galaxies to share the same major axis orientation as their host cluster also extends to the rest of the galaxy
Binggeli B., Ciotti L., Coutts A., Lisa Torlina, Michael J. West, Roberto De Propris, West M. J.   +6 more
core   +2 more sources

The Faraday Scalpel: Electrochemical Nerve Lesioning Mechanisms Studied in Invertebrate Models

Advanced Science, EarlyView.
Direct‐current produces nerve lesioning through discrete electrochemical reactions. Using hypoxia‐sensitive locust nerves and hypoxia‐tolerant leech nerves, we map three injury pathways: cathodic oxygen reduction, cathodic alkalization, and anodic chloride oxidation. These findings establish electrochemical lesioning—the “Faraday Scalpel”—as a precise,
Petra Ondráčková, Jan Švec, Marie Jakešová, Jiří Ehlich, Imrich Gablech, Eric Daniel Głowacki   +5 more
wiley   +1 more source

Treating Disorders of Consciousness With Apomorphine: Protocol for a Double-Blind Randomized Controlled Trial Using Multimodal Assessments

Frontiers in Neurology, 2019
Background: There are few available therapeutic options to promote recovery among patients with chronic disorders of consciousness (DOC). Among pharmacological treatments, apomorphine, a dopamine agonist, has exhibited promising behavioral effects and ...
Leandro R. D. Sanz, Leandro R. D. Sanz, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Séverine Blandiaux, Séverine Blandiaux, Estelle Bonin, Estelle Bonin, Aurore Thibaut, Aurore Thibaut, Aurore Thibaut, Aurore Thibaut, Johan Stender, Neal M. Farber, Ross D. Zafonte, Ross D. Zafonte, Nicholas D. Schiff, Steven Laureys, Steven Laureys, Olivia Gosseries, Olivia Gosseries   +22 more
doaj   +1 more source

A Crack‐Based One‐Dimensional Microspheres Array Enables Thermal–Mechanical Decoupled Dual‐Functional Sensing

Advanced Science, EarlyView.
Inspired by Nostoc, a crack‐based one‐dimensional microspheres array (COMA) sensor is developed, which stabilizes crack geometry under isotropic expansion, enabling a predictable, monotonic thermal response from which true strain can be accurately extracted. The COMA sensor exhibits high sensitivity at ultralow deformation (gauge factor up to 89) and a
Wanqing Xu, Hongyi Tu, Zehao Wang, Tianyu Zhu, Chao Wang, Min Chen, Lan Shi, Limin Wu   +7 more
wiley   +1 more source

Near-UV OH Prompt Emission in the Innermost Coma of 103P/Hartley 2

, 2017
The Deep Impact spacecraft fly-by of comet 103P/Hartley 2 occurred on 2010 November 4, one week after perihelion with a closest approach (CA) distance of about 700 km.
A'Hearn, Michael F., Bodewits, Dennis, Farnham, Tony, Feaga, Lori, Kelley, Michael S. P., La Forgia, Fiorangela, Protopapa, Silvia, Sunshine, Jessica   +7 more
core   +1 more source

Nationwide Real‐World Modeling of Surgical Outcomes in Elderly Patients: Incorporating Geriatric‐Specific Risk Factors Into Prediction of Mortality and Morbidity

Annals of Gastroenterological Surgery, EarlyView.
A reliable and effective risk prediction model for mortality and morbidity in elderly patients undergoing gastroenterological surgeries was developed and validated. Geriatric‐specific risk factors, including the newly added variables in the NCD registry, along with age, were identified as significant contributors to the model. ABSTRACT Aim As the aging
Naoya Sato, Hiraku Kumamaru, Mitsukazu Gotoh, Yoshihiro Kakeji, Yuko Kitagawa, Yasuyuki Seto, Hiromi Rakugi, Masahiro Akishita, Kazue Nakajima, Arata Takahashi, Hiroaki Miyata, Shigeru Marubashi   +11 more
wiley   +1 more source