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Traumatic Brain Injury [PDF]

Seminars in Respiratory and Critical Care Medicine, 2002
Traumatic brain injury (TBI) is a serious health issue in the United States, killing 100,000 people a year and serving as a source of long-term disability for many more. It is the leading cause of death in patients under the age of 45 years. Successful management of TBI requires first an appreciation that a significant part of the neuronal injury ...
Kama, Guluma, Brian, Zink
  +8 more sources

Treatment of Dysphagia with Biofeedback and Functional Electrical Stimulation in a Patient with Wallenberg Syndrome: A Prospective Case Report

Case Reports in Neurology, 2021
Biofeedback games and automated functional electrical stimulation (FES) can be used in the treatment of dysphagia. This case study aims to evaluate the effect of the treatment on a 77-year-old man with chronic Wallenberg syndrome and his and the ...
Daniela Jakobsen, Rainer Seidl, Ingrid Poulsen, Derek John Curtis   +3 more
doaj   +1 more source

Construction of a New 3D Cu(II) Compound with Photocatalytic Activity and Therapeutic Effect on Ventriculitis

Journal of Chemistry, 2022
A new Cu(II) compound, that is {[Cu(L)(ClO4)(H2O)(CH3CN)](ClO4)}n (1, L is 4-(furan-2-yl)-2,6-bis(pyridin-2-yl)pyridine), was solvothermally synthesized and structurally characterized.
Xingzhao Chen, Qing Mao
doaj   +1 more source

Hippocampal interneuronal dysfunction and hyperexcitability in a porcine model of concussion

Communications Biology, 2023
Cognitive impairment is a common symptom following mild traumatic brain injury (mTBI or concussion) and can persist for years in some individuals.
Alexandra V. Ulyanova, Christopher D. Adam, Carlo Cottone, Nikhil Maheshwari, Michael R. Grovola, Oceane E. Fruchet, Jami Alamar, Paul F. Koch, Victoria E. Johnson, D. Kacy Cullen, John A. Wolf   +10 more
doaj   +1 more source

Long-Term Vocational Outcome at 15 Years from Severe Traumatic and Non-Traumatic Brain Injury in Pediatric Age

Brain Sciences, 2023
Background: Recent studies suggest that acquired brain injury with impaired consciousness in infancy is related to more severe and persistent effects and may have a cumulative effect on ongoing development.
Sandra Strazzer, Valentina Pastore, Susanna Frigerio, Katia Colombo, Sara Galbiati, Federica Locatelli, Susanna Galbiati   +6 more
doaj   +1 more source

Traumatic brain injuries [PDF]

Nature Reviews Disease Primers, 2016
Traumatic brain injuries (TBIs) are clinically grouped by severity: mild, moderate and severe. Mild TBI (the least severe form) is synonymous with concussion and is typically caused by blunt non-penetrating head trauma. The trauma causes stretching and tearing of axons, which leads to diffuse axonal injury - the best-studied pathogenetic mechanism of ...
Blennow, K, Brody, DL, Kochanek, PM, Levin, H, McKee, A, Ribbers, GM, Yaffe, K, Zetterberg, H   +7 more
openaire   +7 more sources

Functional role of brain-engrafted macrophages against brain injuries

Journal of Neuroinflammation, 2021
Background Brain-resident microglia have a distinct origin compared to macrophages in other organs. Under physiological conditions, microglia are maintained by self-renewal from the local pool, independent of hematopoietic progenitors.
Xi Feng, Elma S. Frias, Maria S. Paladini, David Chen, Zoe Boosalis, McKenna Becker, Sonali Gupta, Sharon Liu, Nalin Gupta, Susanna Rosi   +9 more
doaj   +1 more source

LRP1 Deficiency Promotes Mitostasis in Response to Oxidative Stress: Implications for Mitochondrial Targeting after Traumatic Brain Injury

Cells, 2023
The brain undergoes oxidative stress and mitochondrial dysfunction following physiological insults such as Traumatic brain injury (TBI), ischemia-reperfusion, and stroke.
Gopal V. Velmurugan, W. Brad Hubbard, Paresh Prajapati, Hemendra J. Vekaria, Samir P. Patel, Alexander G. Rabchevsky, Patrick G. Sullivan   +6 more
doaj   +1 more source

The localization of molecularly distinct microglia populations to Alzheimer's disease pathologies using QUIVER

Acta Neuropathologica Communications, 2023
New histological techniques are needed to examine protein distribution in human tissues, which can reveal cell shape and disease pathology connections.
Ryan K. Shahidehpour, Abraham S. Nelson, Lydia G. Sanders, Chloe R. Embry, Peter T. Nelson, Adam D. Bachstetter   +5 more
doaj   +1 more source

Exploration of eye movement desensitization and reprocessing in treating posttraumatic stress-disorder in patients with acquired brain injury: a retrospective case series

European Journal of Psychotraumatology, 2023
Background: Posttraumatic stress disorder (PTSD) is prevalent in people with acquired brain injury (ABI). Despite the established efficacy of eye movement desensitization and reprocessing (EMDR) for PTSD in general, evaluation studies on EMDR in ABI ...
E.P.J. Janssen, P.J.J. Spauwen, S.J.M. Rijnen, R.W.H.M. Ponds   +3 more
doaj   +1 more source