Results 21 to 30 of about 691,892 (264)

Acute inflammatory profiles differ with sex and age after spinal cord injury

Journal of Neuroinflammation, 2021
Background Sex and age are emerging as influential variables that affect spinal cord injury (SCI) recovery. Despite a changing demographic towards older age at the time of SCI, the effects of sex or age on inflammation remain to be elucidated. This study
Andrew N. Stewart, John L. Lowe, Ethan P. Glaser, Caitlin A. Mott, Ryan K. Shahidehpour, Katelyn E. McFarlane, William M. Bailey, Bei Zhang, John C. Gensel   +8 more
doaj   +1 more source

Astrocytes and Brain Injury [PDF]

Journal of Cerebral Blood Flow & Metabolism, 2003
Astrocytes are the most numerous cell type in the central nervous system. They provide structural, trophic, and metabolic support to neurons and modulate synaptic activity. Accordingly, impairment in these astrocyte functions during brain ischemia and other insults can critically influence neuron survival.
Yongmei, Chen, Raymond A, Swanson
openaire   +2 more sources

A manual-based vocational rehabilitation program for patients with an acquired brain injury: study protocol of a pragmatic randomized controlled trial (RCT)

Trials, 2017
Background An acquired brain injury (ABI) is a complex injury often followed by a broad range of cognitive, physical, emotional, and behavioral disabilities. Because of these disabilities, vocational rehabilitation (VR) is a challenging task, however, of
Louise K. Hoeffding, Maria Haahr Nielsen, Morten A. Rasmussen, Anne Norup, Juan Carlos Arango-Lasprilla, Ulrikka K. Kjær, Kristoffer Sølvsten Burgdorf, Kirsten Jensen Quas, Trine Schow   +8 more
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Sedation-Induced Burst Suppression Predicts Positive Outcome Following Traumatic Brain Injury

Frontiers in Neurology, 2021
While electroencephalogram (EEG) burst-suppression is often induced therapeutically using sedatives in the intensive care unit (ICU), there is hitherto no evidence with respect to its association to outcome in moderate-to-severe neurological patients. We
Joel Frohlich, Micah A. Johnson, David L. McArthur, Evan S. Lutkenhoff, John Dell'Italia, Courtney Real, Vikesh Shrestha, Norman M. Spivak, Jesús E. Ruiz Tejeda, Paul M. Vespa, Martin M. Monti, Martin M. Monti   +11 more
doaj   +1 more source

Apolipoprotein E4 impairs spontaneous blood brain barrier repair following traumatic brain injury

Molecular Neurodegeneration, 2018
Background Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in human TBI patients, yet the molecular mechanisms ...
Bevan S. Main, Sonia Villapol, Stephanie S. Sloley, David J. Barton, Maia Parsadanian, Chinyere Agbaegbu, Kathryn Stefos, Mondona S. McCann, Patricia M. Washington, Olga C. Rodriguez, Mark P. Burns   +10 more
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Correction to: EIF4A3-induced circular RNA MMP9 (circMMP9) acts as a sponge of miR-124 and promotes glioblastoma multiforme cell tumorigenesis

Molecular Cancer, 2020
An amendment to this paper has been published and can be accessed via the original article.
Renjie Wang, Sai Zhang, Xuyi Chen, Nan Li, Jianwei Li, Ruichao Jia, Yuanqing Pan, Haiqian Liang   +7 more
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Ferroptosis and Brain Injury [PDF]

Developmental Neuroscience, 2018
Ferroptosis is a nonapoptotic form of cell death characterized by the iron-dependent accumulation of toxic lipid reactive oxygen species. Small-molecule screening and subsequent optimization have yielded potent and specific activators and inhibitors of this process.
Leslie Magtanong, Scott J. Dixon
openaire   +2 more sources

Growth Hormone Increases BDNF and mTOR Expression in Specific Brain Regions after Photothrombotic Stroke in Mice

Neural Plasticity, 2022
Aims. We have shown that growth hormone (GH) treatment poststroke increases neuroplasticity in peri-infarct areas and the hippocampus, improving motor and cognitive outcomes.
Sonia Sanchez-Bezanilla, Daniel J. Beard, Rebecca J. Hood, N. David Åberg, Patricia Crock, Frederick R. Walker, Michael Nilsson, Jörgen Isgaard, Lin Kooi Ong   +8 more
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Traumatic brain injury [PDF]

Neurology, 2010
In the article “A Prospective Diffusion Tensor Imaging Study in Mild Traumatic Brain Injury” ( Neurology ® 2010;74:643–650), Andrew Mayer and colleagues studied the effects of mild brain injury using a special kind of magnetic resonance image (MRI). The new MRI sequence is called diffusion tensor imaging (DTI).
Emily, Gilmore, Steven, Karceski
openaire   +2 more sources

Hypertonic sodium lactate infusion reduces vasopressor requirements and biomarkers of brain and cardiac injury after experimental cardiac arrest

Critical Care, 2023
Introduction Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective treatments.
Filippo Annoni, Fuhong Su, Lorenzo Peluso, Ilaria Lisi, Enrico Caruso, Francesca Pischiutta, Elisa Gouvea Bogossian, Bruno Garcia, Hassane Njimi, Jean-Louis Vincent, Nicolas Gaspard, Lorenzo Ferlini, Jacques Creteur, Elisa R. Zanier, Fabio Silvio Taccone   +14 more
doaj   +1 more source