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The decrease in mortality and improved outcome for patients with severe traumatic brain injury over the past 25 years can be attributed to the approach of "squeezing oxygenated blood through a swollen brain". Quantification of cerebral perfusion by monitoring of intracranial pressure and treatment of cerebral hypoperfusion decrease secondary injury ...
openaire +2 more sources
Transorbital brain injuries [PDF]
A 20 year old man attended the accident and emergency department after an assault with a short bladed knife. He had sustained a stab wound to the right orbit. There was no other significant history. On examination he was alert and orientated with a Glasgow coma scale of 15.
P, Cackett, J, Stebbing
openaire +2 more sources
Psychological Outcome in Young Survivors of Severe TBI: A Cross-Informant Comparison
Objective. To investigate the psychological outcome and the agreement between self-ratings and proxy-ratings in young individuals after severe traumatic brain injury (TBI). Methods.
Karoline Doser +2 more
doaj +1 more source
Introduction Prognosis after resuscitation from cardiac arrest (CA) remains poor, with high morbidity and mortality as a result of extensive cardiac and brain injury and lack of effective treatments.
Filippo Annoni +14 more
doaj +1 more source
Diverging volumetric trajectories following pediatric traumatic brain injury. [PDF]
Traumatic brain injury (TBI) is a significant public health concern, and can be especially disruptive in children, derailing on-going neuronal maturation in periods critical for cognitive development.
Asarnow, Robert F +10 more
core +3 more sources
Traumatic brain injury (TBI) affects how the brain functions in the short and long term. Resulting patient outcomes across physical, cognitive, and psychological domains are complex and often difficult to predict.
Andrew Tritt +9 more
doaj +1 more source
Iowa Plan for Brain Injury, October 2002 – September 2005 [PDF]
Cutting edge emergency services now allow many Iowans to survive a traumatic brain injury (TBI) that would have caused death just a decade ago.
core
This report describes technical adaptations of a traumatic brain injury (TBI) model-largely inspired by Marmarou-in order to monitor microdialysis data and PtiO2 (brain tissue oxygen) before, during and after injury. We particularly focalize on our model
Bruno Palmier +16 more
core +1 more source
Neuroinflammation and structural injury of the fetal ovine brain following intra-amniotic Candida albicans exposure. [PDF]
BackgroundIntra-amniotic Candida albicans (C. Albicans) infection is associated with preterm birth and high morbidity and mortality rates. Survivors are prone to adverse neurodevelopmental outcomes.
AJ Wolfberg +63 more
core +4 more sources
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

