Results 31 to 40 of about 149,535 (266)

Measures of metabolism and complexity in the brain of patients with disorders of consciousness

NeuroImage: Clinical, 2017
Background: Making an accurate diagnosis in patients with disorders of consciousness remains challenging. 18F-fluorodeoxyglucose (FDG)–PET has been validated as a diagnostic tool in this population, and allows identifying unresponsive patients with a ...
Olivier Bodart, Olivia Gosseries, Sarah Wannez, Aurore Thibaut, Jitka Annen, Melanie Boly, Mario Rosanova, Adenauer G. Casali, Silvia Casarotto, Giulio Tononi, Marcello Massimini, Steven Laureys   +11 more
doaj   +1 more source

Patterns of Postictal Abnormalities in Relation to Status Epilepticus in Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Abnormalities on peri‐ictal diffusion‐weighted magnetic resonance imaging (DWI‐PMAs) are well‐established for patients with status epilepticus (SE), but knowledge on patterns of DWI‐PMAs and their prognostic impact is sparse. Methods This systematic review and individual participant data meta‐analysis included observational studies ...
Andrea Enerstad Bolle, Silvana Sarria‐Estrada, Thomas Bonduelle, Bertram Daniel Dynesen, Manuel Toledo, Zhu Chung Che, Kjell Heuser, Anastasios Chatzikonstantinou, Jérôme Aupy, Udaya Seneviratne, Estevo Santamarina Perez, Christoph Patrick Beier   +11 more
wiley   +1 more source

Reappearance of Command-Following Is Associated With the Recovery of Language and Internal-Awareness Networks: A Longitudinal Multiple-Case Report

Frontiers in Systems Neuroscience, 2019
The recovery of patients with disorders of consciousness is a real challenge, especially at the chronic stage. After a severe brain injury, patients can regain some slight signs of consciousness, while not being able to functionally communicate.
Charlène Aubinet, Rajanikant Panda, Stephen Karl Larroque, Helena Cassol, Mohamed Ali Bahri, Manon Carrière, Sarah Wannez, Steve Majerus, Steven Laureys, Aurore Thibaut   +9 more
doaj   +1 more source

A protocol for a multicenter randomized and personalized controlled trial using rTMS in patients with disorders of consciousness

Frontiers in Neurology, 2023
BackgroundImproving the functional recovery of patients with DoC remains one of the greatest challenges of the field. Different theories exist about the role of the anterior (prefrontal areas) versus posterior (parietal areas) parts of the brain as ...
Marie M. Vitello, Marie M. Vitello, Martin J. Rosenfelder, Martin J. Rosenfelder, Paolo Cardone, Paolo Cardone, Masachika Niimi, Masachika Niimi, Masachika Niimi, Lina Willacker, Aurore Thibaut, Aurore Thibaut, Nicolas Lejeune, Nicolas Lejeune, Nicolas Lejeune, Steven Laureys, Steven Laureys, Steven Laureys, Andreas Bender, Andreas Bender, Olivia Gosseries, Olivia Gosseries   +21 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Personality traits and pattern of beliefs of near-death(-like) experiencers

Frontiers in Human Neuroscience, 2023
IntroductionLittle is known about the potential personality and psychological predictors of near-death experiences (NDEs), and fewer yet those of near-death-like experiences (NDEs-like; similar phenomenology reported after a non-life-threatening context).
Aminata Bicego, Héléna Cassol, Héléna Cassol, Jessica Simon, Pauline Fritz, Pauline Fritz, Simona Abagnale, Audrey Vanhaudenhuyse, Audrey Vanhaudenhuyse, Steven Laureys, Steven Laureys, Steven Laureys, Charlotte Martial, Charlotte Martial   +13 more
doaj   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source

Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li, Guilin Meng, Zijie Wang, Xiao Hu, Jing Cheng, Chu Chen, Tiannan Yang, Jiaxin Luo, Zizhen Meng, Xueyun Liu, Qi Li   +10 more
wiley   +1 more source

Near-Death Experience Memories Include More Episodic Components Than Flashbulb Memories

Frontiers in Psychology, 2020
Memories of near-death experiences (NDEs) are recalled as “realer” than memories of other real or imagined events. Given their rich phenomenology, emotionality and consequentiality, it was hypothesized that they could meet some aspects of the definition ...
Helena Cassol, Helena Cassol, Estelle A. C. Bonin, Estelle A. C. Bonin, Christine Bastin, Ninon Puttaert, Vanessa Charland-Verville, Vanessa Charland-Verville, Steven Laureys, Steven Laureys, Charlotte Martial, Charlotte Martial   +11 more
doaj   +1 more source

Indicators and criteria of consciousness: ethical implications for the care of behaviourally unresponsive patients

BMC Medical Ethics, 2022
Background Assessing consciousness in other subjects, particularly in non-verbal and behaviourally disabled subjects (e.g., patients with disorders of consciousness), is notoriously challenging but increasingly urgent. The high rate of misdiagnosis among
Michele Farisco, Cyriel Pennartz, Jitka Annen, Benedetta Cecconi, Kathinka Evers   +4 more
doaj   +1 more source