Results 41 to 50 of about 776,742 (302)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Monitoring of Hemostasis in Combat Trauma Patients [PDF]

open access: yesMilitary Medicine, 2004
Bleeding is clearly a major cause of morbidity and death after trauma. When bleeding is attributable to transection of major vessels, surgical repair is appropriate. Posttraumatic microvascular bleeding attributable to coagulopathy secondary to metabolic derangements, hypothermia, and depletion or dysfunction of cellular and protein components requires
openaire   +2 more sources

Topical Review: Medical Trauma During Early Childhood [PDF]

open access: yes, 2021
OBJECTIVE: Early childhood is a high-risk period for exposure to traumatic medical events due to injury/illness. It is also one of the most important and vulnerable periods due to rapid development in neurobiological systems, attachment relationships ...
Marsac, M.L.   +11 more
core   +2 more sources

White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian   +8 more
wiley   +1 more source

Neuropsychological profiles of adolescents with a history of childhood trauma [PDF]

open access: yes, 2010
Traumatic events experienced in childhood, such as physical and sexual abuse, can lead to multiple long-term effects on later cognitive functioning. Empirical research has shown that specific brain regions are affected by traumatic stress, including the ...
Ashley-Cooper, Michaela
core   +1 more source

The use of information technologies to predict and diagnose the psychological trauma of servicemen – combatants

open access: yesLaw and Safety, 2018
Based on the analysis of existing developments in the field of automation of psychological and psycho-physiological testing procedures, as well as own empirical studies of combat psychological trauma of servicemen – combatants, the authors within the ...
O. S. Kolesnichenko, S. A. Gorelyshev
doaj   +1 more source

A Trauma System for Ireland: Report of the Trauma Steering Group [PDF]

open access: yes, 2018
Injury is a public health problem of enormous magnitude, whether measured by years of productive life lost, prolonged or permanent disability, or financial cost.
Trauma Steering Group
core  

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Pre-activated lyophilized platelets show non-inferior hemostatic effect compared with fresh platelets in rabbits with traumatic bleeding and shock

open access: yesPlatelets
Background A high activation level is a normal characteristic of lyophilized platelets (LPs); however, the effects of this activation level on the efficacy and safety of LPs after transfusion are debated.Objectives We aimed to test the efficacy and ...
Chenglin Dai   +7 more
doaj   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

open access: yesAdvanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena   +3 more
wiley   +1 more source

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