Results 61 to 70 of about 32,833 (257)
Post-traumatic stress disorder in a military cohort with war trauma
Introduction: People who are part of the armed forces worldwide have been susceptible to the development of post-traumatic stress disorder, due to exposure to conditions that predispose its development.
Alirio Bastidas Goyes +5 more
doaj
Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr +19 more
wiley +1 more source
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng +18 more
wiley +1 more source
Principles of Medical Assistance in Combat Heart Injury in Schemes and Algorithms
Combat injury of the heart and main vessels currently remains a cornerstone in patients with polytrauma. According to the US Department of Defense Trauma Registry, the incidence of heart injuries as a component of chest injuries does not exceed 6 ...
Sergii O. Siromakha, Polyna A. Danchenko
doaj
HLP‐SeNPs, a Lysimachia christinae polysaccharide‐modified selenium nanoparticle, treat kidney stones by downregulating TOMM22 expression, which reduces PINK1 translocation into mitochondria and promotes its retention on the outer mitochondrial membrane.
Junyi Yang +10 more
wiley +1 more source
Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Value of Treatment for Combat Ocular Trauma
Abstract Introduction Combat ocular trauma (COT) represents a significant risk to U.S. warfighters, and the cost of COT can be substantial. We quantified the economic value associated with vision improvements from COT treatment and the potential value of treatment innovation or other ...
Karen Mulligan +4 more
openaire +2 more sources
The biomimetic self‐assembly nanomedicine reversing atherosclerosis via senotherapy strategy. ABSTRACT The greatest challenge in atherosclerosis (AS) management lies in achieving lesion reversal, not merely slowing progression. Senescent cell accumulation—driven by continuous generation and apoptotic resistance—perpetuates plaque pathology and ...
Yuhan Tian +9 more
wiley +1 more source
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding +4 more
wiley +1 more source
Biologic substrates, prepared by decellularizing and solubilizing tissues, have been of great interest in the tissue engineering field because of the preservation of complex biochemical constituents found in the native extracellular matrix (ECM).
Ramon E. Coronado +5 more
doaj +1 more source

