Results 81 to 90 of about 776,742 (302)

Combat Poverty Agency annual report 1996 [PDF]

open access: yes, 1996
This report describes the work undertaken by the Agency in the past year to reduce persistent poverty and social exclusion. The Strategic Plan 1996·98 provides the framework for this work.
Combat Poverty Agency (CPA)
core  

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

Value of Treatment for Combat Ocular Trauma

open access: yesMilitary Medicine
Abstract Introduction Combat ocular trauma (COT) represents a significant risk to U.S. warfighters, and the cost of COT can be substantial. We quantified the economic value associated with vision improvements from COT treatment and the potential value of treatment innovation or other ...
Karen Mulligan   +4 more
openaire   +2 more sources

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Classification system of stress-associated and post-traumatic stress disorders and its justification

open access: yesJournal of Education, Health and Sport, 2017
The objective: to form classification of stress- associative and post-traumatic stress disorders on the base of analysis of their existing theoretical and empirical studies.
Yuriy Danyk, Oleg Druz, Inna Chernenko
doaj  

Compliance with Prehospital Triage Protocols for Major Trauma Patients

open access: yes, 2009
Background: The extent to which severely injured patients receive definitive care at trauma centers is determined by the accuracy of prehospital major trauma criteria in predicting severe injuries and by the level of compliance with these triage ...
Matthew Huei-Ming; MacKenzie, Ellen J.; Alcorta, Richard; Kelen, Gabor D.   +1 more
core  

Photobiomodulation‑Engineered Extracellular Vesicles Enhance Neural Differentiation via UFL1‑Mediated UFMylation in Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang   +12 more
wiley   +1 more source

The Genesis of Long Bone Defects Resulting from Modern Combat Trauma: Part 1. Defect Localization

open access: yesУкраїнський журнал клінічної хірургії
Objective. To characterize the pathogenesis of long bone defects resulting from modern combat trauma as a fundamental basis for developing treatment technologies and protocols for victims. Materials and Methods.
S. O. Guryev   +4 more
doaj   +1 more source

Lofty Ideals Tangible Results: Interim Report by the Projects in the Republic of Ireland in the Second European Programme to Combat Poverty

open access: yes, 1988
This is the first Interim Report of the Projects in the Republic of Ireland in the Second European Programme to Combat Poverty. The projects have been meeting regularly to share experiences and information since they began their work.
Combat Poverty Agency
core  

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang   +11 more
wiley   +1 more source

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