Results 81 to 90 of about 32,833 (257)

The E3 Ubiquitin Ligase RLIM Safeguards Oligodendrocyte Development and Myelination by Targeting SLC7A11 for Polyubiquitination to Regulate Ferroptotic Resistance

Advanced Science, EarlyView.
RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li, Haijun Zhang, Jieya Zhou, Shiyu Yang, Jingmei Cha, Gaofeng Yan, Shuhua Zhao, Bingyu Mao, Pengcheng Ma   +8 more
wiley   +1 more source

The relationship between co-occurring traumatic experiences and co-occurring mental health domains for veterans resident in Northern Ireland

BMC Psychology
Introduction Veterans residing in Northern Ireland (NI) likely experience higher levels of co-occurring lifetime trauma exposure and associated co-occurring mental health symptoms, due to the Troubles.
Catherine Hitch, Erik Spikol, Paul Toner, Cherie Armour   +3 more
doaj   +1 more source

Risk-based characterization of combat abdominal trauma

Український журнал клінічної хірургії
Objective. Formation of a risk-oriented characterization of modern combat abdominal trauma as a fundamental basis for the creation of effective clinical protocols and clinical routes in the process of providing medical care to victims Materials and ...
S. O. Guryev, V. A. Kushnir, O. S. Solovyov, S. I. Panasenko   +3 more
doaj   +1 more source

[Role and prospect of regenerative medicine in early treatment of combat trauma]. [PDF]

Zhonghua Shao Shang Yu Chuang Mian Xiu Fu Za Zhi, 2023
Tian GL, Cheng B, Fu XB.
europepmc   +1 more source

Multiscale Circuit Architecture Associated With Memory Dysfunction in Temporal Lobe Epilepsy

Advanced Science, EarlyView.
A multiscale precision‐mapping framework reveals that memory impairment in temporal lobe epilepsy arises from the convergence of focal medial temporal pathology, strategic white matter disconnection, and limbic‐centered metabolic network dysfunction.
Jiajie Mo, Qiwen Yuan, Pengfei Zhang, Lin Sang, Zhong Zheng, Baotian Zhao, Xiu Wang, Chao Zhang, Wenhan Hu, Xiaoqiu Shao, Jianguo Zhang, Ruijin Yang, Kai Zhang   +12 more
wiley   +1 more source

Peritonitis index caused by abdominal combat trauma

Український журнал військової медицини
Objective: to create a scale for assessing the peritonitis in combat abdominal trauma to determine surgical tactics Materials and methods. An analysis of surgical care and treatment of 227 wounded who received combat abdominal trauma in the ...
I. V. Sobko, V. Ya. Bilyi, S. A. Aslanian, Ya. L. Zarutsky   +3 more
doaj   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

The Enduring Health Consequences of Combat Trauma: a Legacy of Chronic Disease. [PDF]

J Gen Intern Med, 2021
Stewart IJ, Poltavskiy E, Howard JT, Janak JC, Pettey W, Zarzabal LA, Walker LE, Beyer CA, Sim A, Suo Y, Redd A, Chung KK, Gundlapalli A.   +12 more
europepmc   +1 more source

Dual‐Functional Silent‐Region SERS Nanoplatform for Real‐Time Bacterial Tracking and Wound Healing Therapy

Advanced Science, EarlyView.
ABSTRACT Bacterial wound infections, particularly those caused by Escherichia coli and Pseudomonas aeruginosa, are difficult to treat due to biofilm formation, multidrug resistance, and chronic inflammation. Here, we report a multifunctional nanoplatform based on a surface‐enhanced Raman scattering (SERS) probe that enables simultaneous photodynamic ...
Hanbin Deng, Rui Wang, Dianqi Zhang, Wei Zhang, Jaebum Choo, Fabiao Yu, Shaowen Cheng   +6 more
wiley   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source