Results 81 to 90 of about 776,742 (302)
Combat Poverty Agency annual report 1996 [PDF]
This report describes the work undertaken by the Agency in the past year to reduce persistent poverty and social exclusion. The Strategic Plan 1996·98 provides the framework for this work.
Combat Poverty Agency (CPA)
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In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao +12 more
wiley +1 more source
Value of Treatment for Combat Ocular Trauma
Abstract Introduction Combat ocular trauma (COT) represents a significant risk to U.S. warfighters, and the cost of COT can be substantial. We quantified the economic value associated with vision improvements from COT treatment and the potential value of treatment innovation or other ...
Karen Mulligan +4 more
openaire +2 more sources
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang +6 more
wiley +1 more source
Classification system of stress-associated and post-traumatic stress disorders and its justification
The objective: to form classification of stress- associative and post-traumatic stress disorders on the base of analysis of their existing theoretical and empirical studies.
Yuriy Danyk, Oleg Druz, Inna Chernenko
doaj
Compliance with Prehospital Triage Protocols for Major Trauma Patients
Background: The extent to which severely injured patients receive definitive care at trauma centers is determined by the accuracy of prehospital major trauma criteria in predicting severe injuries and by the level of compliance with these triage ...
Matthew Huei-Ming; MacKenzie, Ellen J.; Alcorta, Richard; Kelen, Gabor D. +1 more
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Photobiomodulated microglia release engineered extracellular vesicles that deliver UFL1 to the injured spinal cord. UFL1 competitively binds p53 with MDM2, inhibiting p53 ubiquitination and stabilizing p53 signaling. This dual mechanism simultaneously promotes anti‐inflammatory microglial polarization and directs neural stem cell differentiation toward
Yunxiao Fang +12 more
wiley +1 more source
The Genesis of Long Bone Defects Resulting from Modern Combat Trauma: Part 1. Defect Localization
Objective. To characterize the pathogenesis of long bone defects resulting from modern combat trauma as a fundamental basis for developing treatment technologies and protocols for victims. Materials and Methods.
S. O. Guryev +4 more
doaj +1 more source
This is the first Interim Report of the Projects in the Republic of Ireland in the Second European Programme to Combat Poverty. The projects have been meeting regularly to share experiences and information since they began their work.
Combat Poverty Agency
core
Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source

