Results 231 to 240 of about 1,956,144 (286)

Navigating the Viral Hepatitis Drug Landscape: New Discoveries and Enduring Challenges. A Narrative Review. [PDF]

Infect Dis Ther
Sun HM, Wang XY, Xu HQ, Gao YH.
europepmc   +1 more source

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Applying the Partial Order Continual Reassessment Method to High-Dimensional Treatment Combinations. [PDF]

Stat Med
Chen W, Liu L, Wages NA, Mozgunov P.
europepmc   +1 more source

VS-4718 enhances apoptosis induced by low-dose carfilzomib and overcomes carfilzomib resistance in PSMB5-mutated proteasome inhibitor resistant multiple myeloma. [PDF]

Sci Rep
Leich-Zbat E, Heredia-Guerrero SC, Evers M, Stühmer T, Grieb T, Rauert-Wunderlich H, Bargou RC, Rosenwald A, Chatterjee M, Brünnert D.   +9 more
europepmc   +1 more source

Amantadine-based combination therapy of Parkinson's disease to prevent fluctuation and dyskinesia - experiences from a Parkinson outpatient clinic. [PDF]

Front Aging Neurosci
Oehlwein C, Netzel L, Mittmann K, Oehlwein M, Schulz-Schaeffer WJ.   +4 more
europepmc   +1 more source

Dual-Biosensor for Five Drugs Detection in Precision Oncology. [PDF]

Bionanoscience
Rodino F, Briki M, Buclin T, Guidi M, Carrara S.   +4 more
europepmc   +1 more source

Development of niosomal nanoparticles loaded with cisplatin and vorinostat combination for cancer therapy. [PDF]

PLoS One
Ali H, Lafi Z, Shalan N.
europepmc   +1 more source

Phytochemical profile and chemosensitizing anticancer activity of Mitragyna speciosa and mitragynine. [PDF]

Sci Rep
Kongsila P, Boonmars T, Sriraj P, Prathumtet J, Ruengthanoo PM, Aukkanimart R.   +5 more
europepmc   +1 more source