Multistrain models predict sequential multidrug treatment strategies to result in less antimicrobial resistance than combination treatment [PDF]
Background Combination treatment is increasingly used to fight infections caused by bacteria resistant to two or more antimicrobials. While multiple studies have evaluated treatment strategies to minimize the emergence of resistant strains for single ...
Ahmad, Amais +7 more
core +4 more sources
Pharmacological and non-pharmacological treatments for ARVI
ARVI is one of the most common diseases worldwide. Search for adequate treatment remains an urgent public healthcare problem globally. The main task is still an effective and safe relief of ARVI symptoms, for the purpose of which both pharmacological and
I. L. Lazarevich
doaj +1 more source
Combinations of drugs in the Treatment of Obesity [PDF]
Obesity is a chronic disease associated with excess morbidity and mortality. Clinical treatment, however, currently offers disappointing results, with very high rates of weight loss failure or weight regain cycles, and only two drugs (orlistat and sibutramine) approved for long-term use.
Marcio C. Mancini +6 more
openaire +3 more sources
Combination therapy for cough and bronchial obstruction in childhood
The inflammatory process in the bronchial mucosa of various origins (infectious, allergic, irritative, etc.) cause changes in the sputum production and its rheological properties, slowing of mucociliary clearance.
Yu. L. Mizernitskiy +2 more
doaj +1 more source
Customizing the therapeutic response of signaling networks to promote antitumor responses by drug combinations [PDF]
Drug resistance, de novo and acquired, pervades cellular signaling networks (SNs) from one signaling motif to another as a result of cancer progression and/or drug intervention.
Bown, James L. +4 more
core +5 more sources
Introduction. An actual task of modern medicine is the development of treatment methods of the central nervous system diseases. The solution of this problem was the creation of new, more effective neuropsychotropic drug that shows pronounced ...
L. I. Kucherenko +4 more
doaj +1 more source
A survey of Top 200 Drugs—Inconsistent Practice of Drug Strength Expression for Drugs Containing Salt Forms [PDF]
Many ionizable drugs are developed and marketed as salt forms. However, there are no clear US regulatory guidelines on drug strength labeling for salts. The strengths of some drugs are expressed as salts and some as free acids/bases.
Prohotsky, Daniel, Zhao, Fang
core +2 more sources
Prevention and treatment of acute respiratory viral infections. Place of combination drugs
Acute respiratory infections (ARVI) constitute a group of infectious diseases of viral etiology characterized by lesions of the respiratory tract, predominantly its upper parts, and common clinical symptoms.
I. M. Kosenko
doaj +1 more source
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma. [PDF]
The long-term overall survival of Ewing sarcoma (EWS) patients remains poor; less than 30% of patients with metastatic or recurrent disease survive despite aggressive combinations of chemotherapy, radiation and surgery.
Alturkmani, Hani +11 more
core +3 more sources
Fixed combinations of glaucoma medications [PDF]
The first line treatment in the management of glaucoma is topical medical therapy. Many patients with glaucoma require multiple medications for adequate intraocular pressure control.
Babić Nikola
doaj +1 more source

