Recreational use, analysis and toxicity of tryptamines [PDF]
The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs.
Mannocchi, Giulio +3 more
core +1 more source
Combination drugs in treatment of osteoarthrosis. Efficacy of Theraflex
OA is the most common form of joint disease and a major cause of morbidity and disability. A significant increase in the incidence of the disease is conditioned by rapid population aging and obesity pandemic. The main clinical symptoms of OA are pain and
L. I. Alekseyeva
doaj +1 more source
Polysaccharide-based self-assembling nanohydrogels: An overview on 25-years research on pullulan [PDF]
The aim of this overview is to review the evolution of the studies carried out, during more than 25 years, on nanohydrogels obtained by self-assembling of pullulan (PUL) using several hydrophobization strategies.
ALHAIQUE, Franco +4 more
core +1 more source
Multimodal treatment of influenza and colds
Acute respiratory viral infections (ARVI) are a group of acute infectious respiratory disorders with different etiology though similar epidemiological, pathogenetic and clinical characteristics.
S. S. Yakimova
doaj +1 more source
Caenorhabditis elegans as a model system for studying drug induced mitochondrial toxicity [PDF]
Today HIV-1 infection is recognized as a chronic disease with obligatory lifelong treatment to keep viral titers below detectable levels. The continuous intake of antiretroviral drugs however, leads to severe and even life-threatening side effects ...
Brul, Stanley +5 more
core +5 more sources
Unfortunately, the occurrence of various pathologies in the ENT organs still remains one of the pressing problems in global healthcare. The frequent manifestation of unwanted pathologies forces us to change methods, and sometimes to introduce something ...
Sergey Ya. Kosyakov +2 more
doaj +1 more source
Single exponential decay waveform; a synergistic combination of electroporation and electrolysis (E2) for tissue ablation. [PDF]
BackgroundElectrolytic ablation and electroporation based ablation are minimally invasive, non-thermal surgical technologies that employ electrical currents and electric fields to ablate undesirable cells in a volume of tissue.
Guenther, Enric +4 more
core +2 more sources
Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. [PDF]
To provide advice on the rational use of antimalarial drugs, Médecins Sans Frontières conducted a randomized, an open label efficacy study in Kajo Keji, an area of high transmission of malaria in southern Sudan.
Epicentre +13 more
core +2 more sources
Knowledge Graph Completion to Predict Polypharmacy Side Effects
The polypharmacy side effect prediction problem considers cases in which two drugs taken individually do not result in a particular side effect; however, when the two drugs are taken in combination, the side effect manifests. In this work, we demonstrate
AM Manicone +10 more
core +1 more source
Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John +5 more
core +1 more source

