Results 111 to 120 of about 252,941 (311)

Bayesian Combination of State Polls and Election Forecasts [PDF]

open access: yes, 2010
A wide range of potentially useful data are available for election forecasting: the results of previous elections, a multitude of pre-election polls, and predictors such as measures of national and statewide economic performance.
Gelman, Andrew E., Lock, Kari
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Road Traffic Congestion Management Based on a Search-Allocation Approach

open access: yesTransport and Telecommunication, 2017
This paper introduces a new scheme for road traffic management in smart cities, aimed at reducing road traffic congestion. The scheme is based on a combination of searching, updating, and allocation techniques (SUA). An SUA approach is proposed to reduce
Raiyn Jamal
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Model selection for forecast combination [PDF]

open access: yes
In this paper it is advocated to select a model only if it significantly contributes to the accuracy of a combined forecast. Using hold-out-data forecasts of individual models and of the combined forecast, a useful test for equal forecast accuracy can be
Franses, Ph.H.B.F.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

AI‐Based Ensemble Flood Forecasts and Its Implementation in Multi‐Objective Robust Optimization Operation for Reservoir Flood Control

open access: yesWater Resources Research
Informing reservoirs with forecasts is highly important for real‐time flood control. This study proposed a forecast‐informed methodology framework for reservoir flood control operation under uncertainty.
Yuxue Guo   +4 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Forecasting Economic and Financial Variables with Global VARs [PDF]

open access: yes
This paper considers the problem of forecasting real and financial macroeconomic variables across a large number of countries in the global economy.
L. Vanessa Smith   +2 more
core  

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