Results 91 to 100 of about 3,298,073 (275)
Advances in Virus Detection Techniques Based on Recombinant Polymerase Amplification
MoleculesRecombinase polymerase amplification (RPA) has emerged as a rapid, efficient, and highly sensitive method for nucleic acid amplification, thus becoming a focal point of research in the field of virus detection.
Shiwen Wu +7 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
Case Reports in Medicine, 2017 Various surgical techniques have been described for the fixation of acromioclavicular (AC) dislocations. However, recurrent dislocation is one of the main complications associated with the majority of these techniques.
Patrick Holweg +6 more
doaj +1 more source
Jurnal Pendidikan Jasmani dan Olahraga, 2019 Volleyball uses a lot of anaerobic energy which can produce a lot of lactic acid that causes fatigue. Recovery is an important factor in increasing an athlete performance.
Dian Helaprahara +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Identifying and Prioritizing the Components of Disciplinary Behavior (Case Study: University Faculty Members) [PDF]
فرایند مدیریت و توسعهPurpose: Employee discipline is one of the important and long-standing concepts in management, which has even continued in postmodern management approaches. The current article aimed to identify the components of the disciplinary behavior of the academic
masoumeh mohammadi +3 more
doaj
Novìtnâ Osvìta, 2018 The article is an in-depth research of the dubbed American feature films small syntax on the basis of the structural and comparative analysis of the original film texts and their Ukrainian translations. The paper considers the functioning of small syntax
Yuliia Pletenetska
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Intrapulmonary distribution of blood flow during exercise in pulmonary hypertension assessed by a new combination technique. [PDF]
Front Cardiovasc Med, 2023 Farina S +4 more
europepmc +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source