Results 141 to 150 of about 9,546,669 (393)

Serum and Vaccine Therapy in Combination with Sulphanilamide or M and B 693 [PDF]

, 1939
Alexander Fleming
openalex   +1 more source

Sensitization of Drug Resistant Cancer Cells: A Matter of Combination Therapy

Cancers, 2018
Cancer drug resistance is an enormous problem. It is responsible for most relapses in cancer patients following apparent remission after successful therapy.
M. Leary, S. Heerboth, K. Lapinska, S. Sarkar   +3 more
semanticscholar   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients

Vascular Health and Risk Management, 2010
Maurizio Destro1, Nora Crikelair2, Joseph Yen2, Robert Glazer 1Azienda Ospedaliera della Provincia di Pavia, Stradella (PV), Italy; 2Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, USAObjective: This post hoc analysis evaluated ...
Maurizio Destro, Nora Crikelair, Joseph Yen, et al.   +3 more
doaj  

All organic nanomedicine for PDT–PTT combination therapy of cancer cells in hypoxia

Scientific Reports
Photodynamic and photothermal therapies are promising treatments for cancer, dermatological, and ophthalmological conditions. However, photodynamic therapy (PDT) is less effective in oxygen-deficient tumor environments.
Anel Urazaliyeva, Perizat Kanabekova, Almaz Beisenbayev, Gulsim Kulsharova, Timur Atabaev, Sehoon Kim, Chang-Keun Lim   +6 more
doaj   +1 more source

Successful transition from Treprostinil to Selexipag in patient with severe pulmonary arterial hypertension

BMC Pulmonary Medicine, 2017
Background In this report, we describe the first successful case of transition from subcutaneous administration of treprostinil to selexipag in a patient with severe pulmonary arterial hypertension (PAH), by evaluating hemodynamic changes and exercise ...
Asuka Furukawa, Yuichi Tamura, Hiroya Iwahori, Masato Goto, Narutaka Ohashi, Teruo Okabe, Akio Kawamura   +6 more
doaj   +1 more source

Combination Therapy of Malignant Hemangioendothelioma with Radiation and Methotrexate [PDF]

, 1962
George A. Hyman, Frederic P. Herter, Ruth Guttmann   +2 more
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Olanzapine and fluoxetine combination therapy for treatment-resistant depression: review of efficacy, safety, and study design issues

Neuropsychiatric Disease and Treatment, 2009
William V Bobo, Richard C SheltonDepartment of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USAAbstract: Treatment-resistant depression (TRD) is a common occurrence in clinical practice.
William V Bobo, Richard C Shelton   +1 more
doaj  

Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy

Frontiers in Immunology, 2018
Immune checkpoint inhibitors (ICIs) have recently revolutionized cancer treatment, providing unprecedented clinical benefits. However, primary or acquired therapy resistance can affect up to two-thirds of patients receiving ICIs, underscoring the urgency
Yiyi Yan, Anagha Bangalore Kumar, Heidi Finnes, Svetomir N. Markovic, Sean Park, Roxana S. Dronca, Haidong Dong, Haidong Dong   +7 more
doaj   +1 more source