Results 231 to 240 of about 1,454,174 (267)

Prostate-Specific Membrane Antigen-Targeted Therapy in Prostate Cancer: History, Combination Therapies, Trials, and Future Perspective

Francesco Mattana, Lorenzo Muraglia, Antonio Barone, Marzia Colandrea, Yasmina Saker Diffalah, S Provera, Alfio Severino Cascio, Emanuela Omodeo Salè, Francesco Ceci   +8 more
openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Complete Resolution of Cutaneous Leishmaniasis With a Novel Topical Combination Therapy: A Case Series. [PDF]

Clin Case Rep
Haghshenas H, Ghanaatpisheh A, Darayesh M, Entezar Almahdi E.   +3 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Efficacy and safety of PEG-IFN α-2b and tenofovir amibufenamide in combination therapy for chronic hepatitis B. [PDF]

BMC Infect Dis
Zhao W, Li L, Liu S, Zhang W, Gao Y, Zhao Z, Liu X, Luo Y, Li D, Liu C.   +9 more
europepmc   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Efficacy and safety of pioglitazone versus dapagliflozin as an add-on to metformin and alogliptin combination therapy: the EPIDOTE study. [PDF]

Sci Rep
Kim K, Ko SH, Yun JS, Lee KW, Kim ES, Jeong IK, Kim JH, Kim SY, Won KC, Kim M, Cha BS, Kim S, Choi SH, Rhee EJ, Kim SG, Kim BH, Park KS, Ju YC, Heo TW, Ahn YB.   +19 more
europepmc   +1 more source

Harnessing combination therapy: Current treatments, recent advancements, and future directions in Alzheimer's disease. [PDF]

J Prev Alzheimers Dis
Fillit HM, Touchon J, Vellas B, Nisenbaum LK, Burstein AH.   +4 more
europepmc   +1 more source

Clinical efficacy of ulinastatin and budesonide combination therapy in pelvic fracture complicated by pulmonary contusion. [PDF]

Eur J Med Res
Lu H, Jia J, Ma X, Li D, Hu Y.
europepmc   +1 more source

Overcoming the drug resistance barrier: progress in fosfomycin combination therapy against multidrug-resistant pathogens. [PDF]

Front Microbiol
Wu Y, Li J, Qiao F, Guo J, Zhang L, Jia X.   +5 more
europepmc   +1 more source