Combination therapy with oncolytic viruses for lung cancer treatment. [PDF]
Sun L, Zhao Q, Miao L.
europepmc +1 more source
A combination therapy of CO2 and YAG Laser for Head and Neck cancer
Tetsuzo Inoue+3 more
openalex +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski+19 more
wiley +1 more source
Combination Therapy Approaches to Enhance the Efficacy of ERV-Targeting Vaccines in Cancer. [PDF]
Gracia-Hernandez M+3 more
europepmc +1 more source
Clinical and biologic effects of combination therapy with gamma-interferon and tumor necrosis factor [PDF]
Joan H. Schiller+11 more
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This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau+9 more
wiley +1 more source
Two cases of disseminated trichosporon beigelii infection treated with combination antifungal therapy [PDF]
Kíyoyuki Ogata+6 more
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
The Future of Chronic Kidney Disease Treatment: Combination Therapy (Polypill) or Biomarker-Guided Personalized Intervention? [PDF]
Biglari S+5 more
europepmc +1 more source