Results 251 to 260 of about 2,643,192 (369)

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Development of CD73 Inhibitors in Tumor Immunotherapy and Opportunities in Imaging and Combination Therapy. [PDF]

J Med Chem
Bi C, Patel JS, Liang SH.
europepmc   +1 more source

Therapeutic Evaluation of Combination Therapy using C-425, Human Native Immunoglobulin Liquid Preparation for i.v. Administration, with Antibiotics in Severe Infections in the Field of Surgery

, 1990
Yoshio Mishima, Toshinao INOUE, Hiroshi Hayasaka, Morio Totsuka, T Ebata, Ryoichi Motoki, Hitoshi Inoue, Yukio Endo, Shoetsu Tamakuma, Jun Imai, Yasuhiko Morioka, M Ishiyama, Chiyuki Watanabe, Kozaburo KIMURA, Shigekatsu KURIHARA, Atsushi NAKAZIMA, Kyuya Ishibiki, Naoki Aikawa, Hiroshi Takagi, N. Taira, Kazue Ozawa, Yasuyuki Shimahara, Takesada Mori, Junichi Kanbayashi, Yoichi Saito, Hiroyasu NISHIYAMA   +25 more
openalex   +2 more sources

Hydrophobicity causes anomalous migration of cystine/glutamate antiporter SLC7A11 in SDS‐PAGE with low acrylamide concentration

FEBS Open Bio, EarlyView.
SLC7A11 frequently migrates faster in SDS‐PAGE. The present study found that the high hydrophobicity of SLC7A11 causes its anomalous migration in SDS‐PAGE with a low concentration of acrylamide gel. Replacing isoleucine with asparagine reduced hydrophobicity and restored its normal migration at 55 kDa, revealing the role of hydrophobicity and gel ...
Nsengiyumva Emmanuel, Qian He, Yixin Kang, Dianbao Zhang, Min Gao, Minglin Wang, Kexin Fan, Jingwen Xiong, Shaobo Wu, Botao Fa, Zhengtao Xiao, Yingfang Niu, Jun Yao, Yilei Zhang   +13 more
wiley   +1 more source

Antibiotic Tolerance and Combination Therapy

mBio, 2015
David C. Bean, Sarah M. Wigmore
doaj   +1 more source

Nephrotoxicity of Immune Checkpoint Inhibitors in Single and Combination Therapy-A Systematic and Critical Review. [PDF]

Biomedicines
Tascón J, Casanova AG, Vicente-Vicente L, López-Hernández FJ, Morales AI.   +4 more
europepmc   +1 more source

A case report about adult Still's disease of chronic polycyclic systemic type which showed effective combination "Saireto" therapy with predonisolon.

, 1991
Yoji Kobayashi, Akiro Terashi
openalex   +2 more sources

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Case report: late adverse reactions in an epilepsy patient on combination therapy with valproate and lamotrigine. [PDF]

Acta Epileptol
Sang H, Zhao L, Zhang Y, Wang X, Zhang X.   +4 more
europepmc   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

FEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli, Andrea Spinaci, Cui Chang, Rosaria Volpini, Catia Lambertucci, Matteo Landriscina, Vincenza Conteduca, Consuelo Amantini, Cristina Aguzzi, Laura Zeppa, Martina Giangrossi, Laura Soverchia, Matteo Santoni, Massimo Nabissi, Giorgio Santoni, Carlo Polidori   +15 more
wiley   +1 more source