Results 181 to 190 of about 13,959 (300)
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Veliko naprav v elektromehaniki uporablja sistem prikazovanja pozicij z odpiranjem in zapiranjem stikal. Če ta naprava uporablja binarno kodo, so možnosti za napačno branje pozicije bitov in posledično napačen izhod podatka, velike. Ker se binarne besede
Vidner, Maja
core
Structural characteristics and evolutionary trajectories of knowledge recombination in the field of AI-driven drug discovery. [PDF]
Xiao J, Li T, Luan Y, Chen X.
europepmc +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Cover-free families on hypergraphs and combinatorial group testing. [PDF]
Idalino TB, Moura L.
europepmc +1 more source
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Unbiased and error-detecting combinatorial pooling experiments with balanced constant-weight Gray codes for consecutive positives detection. [PDF]
He G +6 more
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Assessing data quality of inflammatory bowel disease patients in the <i>All of Us</i> research program. [PDF]
Spotnitz M +5 more
europepmc +1 more source

