Results 161 to 170 of about 13,959 (300)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Regular low-density parity-check codes from combinatorial designs

open access: yes
Analytically constructed LDPC codes comprise only a very small subset of possible codes and as a result LDPC codes are still, for the most part, constructed randomly.
Sarah Johnson (21132320)   +1 more
core  

Full weight spectrum one-orbit cyclic subspace codes

open access: yes
For a linear Hamming metric code of length n over a finite field, the number of distinct weights of its codewords is at most n. The codes achieving the equality in the above bound were called full weight spectrum codes.
Polverino O., Zullo F., Castello C.
core   +1 more source

Robust parent-identifying codes and combinatorial arrays [PDF]

open access: yes, 2011
An $n$-word $y$ over a finite alphabet of cardinality $q$ is called a descendant of a set of $t$ words $x^1,\dots,x^t$ if $y_i\in\{x^1_i,\dots,x^t_i\}$ for all $i=1,\dots,n.$ A code $\cC=\{x^1,\dots,x^M\}$ is said to have the $t$-IPP property if for any $
Grigory Kabatiansky, Alexander Barg
core  

Binary De Bruijn sequences for DS-CDMA systems: analysis and results

open access: yesEURASIP Journal on Wireless Communications and Networking, 2011
Code division multiple access (CDMA) using direct sequence (DS) spread spectrum modulation provides multiple access capability essentially thanks to the adoption of proper sequences as spreading codes.
Spinsante Susanna   +2 more
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Multirate DS/CDMA Systems with Heuristic-Genetic Detector in Multipath Channels

open access: yesSemina: Ciências Exatas e Tecnológicas, 2005
This work analyses a combinatorial optimization technique based on genetic algorithm (GA) applied to the multiuser detection problem (MuD) in multirate DS/CDMA systems by multiple codes in multipath fading channels.
Taufik Abrão   +2 more
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Combinatorial Properties of Frameproof and Traceability Codes

open access: yes, 2000
In order to protect copyrighted material, codes may be embedded in the content or codes may be associated with the keys used to recover the content. Codes can offer protection by providing some form of traceability for pirated data. Several researchers
R. Wei   +5 more
core  

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