Results 141 to 150 of about 13,959 (300)

Gray codes and lexicographical combinatorial generation for nonnesting and sparse nonnesting set partitions

open access: yes, 2015
We present combinatorial Gray codes and explicit designs of efficient algorithms for lexicographical combinatorial generation of the sets of nonnesting and sparse nonnesting set partitions of length ...
Conflitti, Alessandro, Mamede, Ricardo
core   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Fingerprinting Codes and Related Combinatorial Structures [PDF]

open access: yes, 2015
Fingerprinting codes were introduced by Boneh and Shaw in 1998 as a method of copyright control. The desired properties of a good fingerprinting code has been found to have deep connections to combinatorial structures such as error-correcting codes and ...
Chuan Guo, Guo, Chuan
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Combinatorial problems motivated by comma-free codes

open access: yes, 2004
In the paper some combinatorial problems motivated by comma-free codes are considered. We describe these problems, give the most significant known results and methods used, present some new results and formulate open ...
Vladimir I. Levenshtein
core  

More on codes for combinatorial composite DNA

open access: yesDesigns, Codes and Cryptography
Abstract In this paper, we focus on constructing unique-decodable and list-decodable codes for the recently studied (t, e)-composite-asymmetric error-correcting codes ((t, e)-CAECCs). Let $$\mathcal {X}$$ X be an
Zuo Ye   +4 more
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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