Results 131 to 140 of about 692,674 (293)
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Matrix bids in combinatorial auctions: expressiveness and micro-economic properties [PDF]
A combinatorial auction is an auction where multiple items are for sale simultaneously to a set of buyers. Furthermore, buyers are allowed to place bids on subsets of the available items.
Spieksma, F.C.R. +2 more
core
New results on Erasure Combinatorial Batch Codes
, 2023 We investigate in this work the problem of Erasure Combinatorial Batch Codes, in which $n$ files are stored on $m$ servers so that every set of $n-r$ servers allows a client to retrieve at most $k$ distinct files by downloading at most $t$ files from ...
Le, Phuc-Lu +3 more
core
Space-Time Codes and Concatenated Channel Codes for Wireless Communications
, 2002 Following a brief historical perspective on channel coding, an introduction to space–time block codes is given. The various space–time codes considered are then concatenated with a range of channel codecs, such as convolutional and block-based turbo ...
Liew, T.H., Hanzo, Lajos
core +1 more source
Transcriptional selectors, masters, and combinatorial codes: regulatory principles of neural subtype specification. [PDF]
Wiley Interdiscip Rev Dev Biol, 2015 Allan DW, Thor S.
europepmc +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
More on codes for combinatorial composite DNA
Designs, Codes and CryptographyAbstract In this paper, we focus on constructing unique-decodable and list-decodable codes for the recently studied (t, e)-composite-asymmetric error-correcting codes ((t, e)-CAECCs). Let $$\mathcal {X}$$ X be an
Zuo Ye +4 more
openaire +2 more sources