Results 111 to 120 of about 692,674 (293)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Applications of perfect difference codes in fiber-optics and wireless optical code-division multiplexing/multiple-access systems [PDF]

, 2012
After establishing itself in the radio domain, Spread spectrum code-division multiplexing/multiple-access (CDMA) has seen a recent upsurge in optical domain as well.
Umrani, Fahim Aziz
core  

Moving forward with combinatorial interaction testing [PDF]

, 2013
Combinatorial interaction testing (CIT) is an efficient and effective method of detecting failures that are caused by the interactions of various system input parameters. In this paper, we discuss CIT, point out some of the difficulties of applying it in
Demiröz, Gülşen, Porter, Adam, Fouche, Sandro, Cohen, Myra B., Yılmaz, Cemal, Koç, Uğur   +5 more
core   +1 more source

Cavity Quantum Electrodynamics (CQED)-Based Quantum LDPC Encoders and Decoders

IEEE Photonics Journal, 2011
Quantum information processing (QIP) relies on delicate superposition states that are sensitive to interactions with environment, resulting in errors. Moreover, the quantum gates are imperfect so that the use of quantum error correction coding (QECC) is ...
Ivan B. Djordjevic
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Combinatorial aspects of code loops

, 2000
6 ...
openaire   +3 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Combinatorial solid-phase synthesis of 4,6-diaryl and 4-aryl, 6-alkyl-1,3,5-triazines and their application to efficient biofuel production

, 2012
10.1021/co300007aACS Combinatorial Science147395 ...
Kim, Jaoon Y. H., Lee, Y., Chang, Young-Tae, Ha, H.-H., Lee, Woo Sirl, Lee, J.W., Chang, Y.-T., Bork, J.T., Lee, W.S., Vendrell, M., Ha, Hyung-Ho, Kim, J.Y.H., Lee, Y, Bork, Jacqueline T., Lee, Jae Wook, Vendrell, Marc   +15 more
core   +1 more source

Approximate Solutions of Combinatorial Problems via Quantum Relaxations

IEEE Transactions on Quantum Engineering
Combinatorial problems are formulated to find optimal designs within a fixed set of constraints and are commonly found across diverse engineering and scientific domains.
Bryce Fuller, Charles Hadfield, Jennifer R. Glick, Takashi Imamichi, Toshinari Itoko, J. Richard Thompson, Yang Jiao, M. Marna Kagele, W. Blom-Schieber Adriana, Rudy Raymond, Antonio Mezzacapo   +10 more
doaj   +1 more source