Results 121 to 130 of about 692,674 (293)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

PSO-Guided Construction of MRD Codes for Rank Metrics

Mathematics
Maximum Rank-Distance (MRD) codes are a class of optimal error-correcting codes that achieve the Singleton-like bound for rank metric, making them invaluable in applications such as network coding, cryptography, and distributed storage.
Behnam Dehghani, Amineh Sakhaie
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

An Agent Based Market Design Methodology for Combinatorial Auctions [PDF]

Auction mechanisms have attracted a great deal of interest and have been used in diverse e-marketplaces. In particular, combinatorial auctions have the potential to play an important role in electronic transactions.
Kun Chang Lee, Gyoo Gun Lim, Jinho Choi
core  

Combinatorial batch codes [PDF]

, 2008
In this paper, we study batch codes, which were introduced by Ishai, Kushilevitz, Ostrovsky and Sahai. A batch code specifies a method to distribute a database of n items among m devices (servers) in such a way that any k items can be retrieved by ...
R. Wei, D. R. Stinson, M. B. Paterson
core  

Construction of Binary Locally Repairable Codes with Nonuniform Locality and Availability Using Combinatorial Designs

Entropy
In this paper, we generalize the construction of locally repairable codes (LRCs) by leveraging pairwise balanced designs (PBDs) and balanced incomplete block designs (BIBDs) to construct codes with nonuniform locality or nonuniform availability.
Yu Zhang, Xiangqiong Zeng
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Construction of Multi-Rate QC-LDPC Codes Based on Permutation Method

Axioms
This paper proposes a systematic permutation-based construction method for multi-rate quasi-cyclic low-density parity-check (QC-LDPC) codes. We first present a graph-theoretic framework in which any regular QC-LDPC code can be normalized to a canonical ...
Hengzhou Xu, Jinru Wang, Mei Zhang, Mengmeng Xu, Qian Wang   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source