Results 101 to 110 of about 13,959 (300)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Multilevel structured low-density parity-check codes for AWGN and Rayleigh channels
, 2010 We propose a novel class of protograph low-density parity-check (LDPC) codes having a combinatorial rather than a random structure, which are termed multilevel-structured (MLS) LDPC codes. It is demonstrated that they posses a strikingly simple structure
Chen, Sheng +2 more
core
Characterization of small trapping sets in LDPC codes from Steiner triple systems
, 2022 S.93-97The error-floor performance of low-density paritycheck (LDPC) codes under iterative decoding is governed by combinatorial configurations in the Tanner graph of the code termed trapping sets.
Milenkovic, O. +2 more
core +1 more source
On a Combinatorial Problem for the Set of Binary Vectors
Известия Иркутского государственного университета: Серия "Математика", 2015 In this paper we introduce a new combinatorial problem for covering binary sets. This problem appears in connection to research of complexity of ESOP.
K.D. Kirichenko
doaj
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
PRX QuantumWe develop a framework for constructing quantum error-correcting codes and logical gates for three types of spaces—composite permutation-invariant spaces of many qubits or qudits, composite constant-excitation Fock state spaces of many bosonic modes, and
Arda Aydin +2 more
doaj +1 more source
Recursive Quantum Relaxation for Combinatorial Optimization Problems [PDF]
QuantumQuantum optimization methods use a continuous degree-of-freedom of quantum states to heuristically solve combinatorial problems, such as the MAX-CUT problem, which can be attributed to various NP-hard combinatorial problems.
Ruho Kondo +3 more
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source